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InterPro: IPR005089 Glycoside hydrolase, family 18, carbohydrate-binding

Protein matchesHelp
UniProtKB
Matches:
21 proteins
AccessionHelp IPR005089 Glyco_hydro_18_carb-bd
TypeHelp Domain
SignaturesHelp
GO Term annotationHelp
Process GO:0006032 chitin catabolic process
Function GO:0004568 chitinase activity
InterPro annotation
BioMart Logo Entry Details in BioMart
AbstractHelp

O-Glycosyl hydrolases EC:3.2.1. are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycosyl hydrolases, based on sequence similarity, has led to the definition of 85 different families [1, 2, 3]. This classification is available on the CAZy (CArbohydrate-Active EnZymes) web site [4]. Because the fold of proteins is better conserved than their sequences, some of the families can be grouped in clans.

Carbohydrate-binding module, family 25 CAZy GH_25 has a starch-binding function as demonstrated in one case.

Database linksHelp
Enzyme: EC:3.2.1.14
CAZy: GH25
PANDIT: PF03427
Blocks: IPB005089
Pfam Clan: CL0155.7

Taxonomic coverageHelp

Example proteinsHelp
P29025 Chitinase 1

P29029 Endochitinase

More proteins


Example Proteins Key


InterPro entry accession number/name and structure databases Colour code
IPR013781 Glycoside hydrolase, subgroup, catalytic core
IPR017853 Glycoside hydrolase, catalytic core
IPR005089 Glycoside hydrolase, family 18, carbohydrate-binding
IPR001579 Glycoside hydrolase, chitinase active site
IPR001223 Glycoside hydrolase, family 18, catalytic domain
SWISS-MODEL
PDB Chain
ModBase
CATH Domain

PublicationsHelp
1. Henrissat B, Callebaut I, Fabrega S, Lehn P, Mornon JP, Davies G.
Conserved catalytic machinery and the prediction of a common fold for several families of glycosyl hydrolases.
Proc. Natl. Acad. Sci. U.S.A. 92 7090-4 1995 [PubMed: 7624375]
http://www.pubmedcentral.nih.gov/picrender.fcgi?tool=EBI&pubmedid=7624375&action=stream&blobtype=pdf
2. Davies G, Henrissat B.
Structures and mechanisms of glycosyl hydrolases.
Structure 3 853-9 1995 [PubMed: 8535779]
http://dx.doi.org/10.1016/S0969-2126(01)00220-9
3. Bairoch A.
Classification of glycosyl hydrolase families and index of glycosyl hydrolase entries in SWISS-PROT.
1999
4. Henrissat B, Coutinho PM.
Carbohydrate-Active Enzymes server.
1999

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InterPro 23.1