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InterPro: IPR004834 Chitin synthase

Protein matches Help

UniProtKB

Matches:

568 proteins

Overview:	sorted by AC,	sorted by name,	of known structure,	proteins with splice variants
Detailed:	sorted by AC,	sorted by name,	of known structure	proteins with splice variants
Table:	For all matching proteins,	of known structure
Architectures
Accession List
Matches in BioMart

Accession

IPR004834 Chitin_synth

Secondary

IPR002923

Type

Family

Signatures Help

Database	ID	Name	Proteins
ProDom	PD002998	Chitin_synth	536
Pfam	PF01644	Chitin_synth_1	567
Signatures in BioMart

GO Term annotation Help

Process

GO:0006031 chitin biosynthetic process

Function

GO:0004100 chitin synthase activity

InterPro annotation

Entry Details in BioMart

Abstract

This region is found commonly in chitin synthases classes I, II and III EC:2.4.1.16. Chitin a linear homopolymer of GlcNAc residues, it is an important component of the cell wall of fungi and is synthesised on the cytoplasmic surface of the cell membrane by membrane bound chitin synthases [1].

Database links Help

Enzyme: EC:2.4.1.16

PANDIT: PF01644

Blocks: IPB004834

Pfam Clan: CL0110.8

Taxonomic coverage Help

Example proteins Help

O74756 Chitin synthase-like protein 2

P08004 Chitin synthase 1

P48017 Chitin synthase

More proteins

Example Proteins Key

InterPro entry accession number/name and structure databases		Colour code
IPR004834	Chitin synthase
IPR004835	Fungal chitin synthase
IPR013616	Chitin synthase N-terminal
	ModBase

Publications Open in usermanual
1.	Georgopapadakou NH, Tkacz JS. The fungal cell wall as a drug target. Trends Microbiol. 3 98-104 1995 [PubMed: 7773595] http://dx.doi.org/10.1016/S0966-842X(00)88890-3

Additional Reading Open in usermanual
	Nino-Vega GA, Buurman ET, Gooday GW, San-Blas G, Gow NA. Molecular cloning and sequencing of a chitin synthase gene (CHS2) of Paracoccidioides brasiliensis. Yeast 14 1998 181-7 [PubMed: 9483806] http://dx.doi.org/10.1002/(SICI)1097-0061(19980130)14:2<181::AID-YEA202>3.3.CO;2-4
	Bowen AR, Chen-Wu JL, Momany M, Young R, Szaniszlo PJ, Robbins PW. Classification of fungal chitin synthases. Proc. Natl. Acad. Sci. U.S.A. 89 1992 519-23 [PubMed: 1731323] http://www.pubmedcentral.nih.gov/picrender.fcgi?tool=EBI&pubmedid=1731323&action=stream&blobtype=pdf

InterPro 23.1