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InterPro: IPR004147 ABC-1

Protein matches Help

UniProtKB

Matches:

2580 proteins

Overview:	sorted by AC,	sorted by name,	of known structure,	proteins with splice variants
Detailed:	sorted by AC,	sorted by name,	of known structure	proteins with splice variants
Table:	For all matching proteins,	of known structure
Architectures
Accession List
Matches in BioMart

Accession

IPR004147 ABC_1

Type

Domain

Signatures Help

Database	ID	Name	Proteins
Pfam	PF03109	ABC1	2580
Signatures in BioMart

InterPro Relationships Help

Parent

IPR011009 Protein kinase-like domain

Found in

IPR010232 2-polyprenylphenol 6-hydroxylase

InterPro annotation

Entry Details in BioMart

Abstract

This entry includes ABC1 from yeast [1] and AarF from Escherichia coli [2]. These proteins have a nuclear or mitochondrial subcellular location in eukaryotes. The exact molecular functions of these proteins is not clear, however yeast ABC1 suppresses a cytochrome b mRNA translation defect and is essential for the electron transfer in the bc 1 complex [1] and E. coli AarF is required for ubiquinone production [2]. It has been suggested that members of the ABC1 family are novel chaperonins [1]. These proteins are unrelated to the ABC transporter proteins.

Database links Help

PANDIT: PF03109

Blocks: IPB004147

Pfam Clan: CL0016.18

Taxonomic coverage Help

Overlapping InterPro entries Help

IPR004147

Numbers of overlapping proteins

Average numbers of overlapping amino acids

Example proteins Help

O04212 Putative ABC1 protein At2g40090

P27697 Protein ABC1, mitochondrial

Q18486 Ubiquinone biosynthesis protein coq-8

Q3MIX3 Uncharacterized aarF domain-containing protein kinase 5

Q566J8 Uncharacterized aarF domain-containing protein kinase 4

More proteins

Example Proteins Key

InterPro entry accession number/name and structure databases		Colour code
IPR011009	Protein kinase-like domain
IPR004147	ABC-1
	ModBase

Publications Open in usermanual
1.	Bousquet I, Dujardin G, Slonimski PP. ABC1, a novel yeast nuclear gene has a dual function in mitochondria: it suppresses a cytochrome b mRNA translation defect and is essential for the electron transfer in the bc 1 complex. EMBO J. 10 2023-31 1991 [PubMed: 1648478] http://ukpmc.ac.uk/picrender.cgi?tool=EBI&pubmedid=1648478&action=stream&blobtype=pdf
2.	Macinga DR, Cook GM, Poole RK, Rather PN. Identification and characterization of aarF, a locus required for production of ubiquinone in Providencia stuartii and Escherichia coli and for expression of 2'-N-acetyltransferase in P. stuartii. J. Bacteriol. 180 128-35 1998 [PubMed: 9422602] http://ukpmc.ac.uk/picrender.cgi?tool=EBI&pubmedid=9422602&action=stream&blobtype=pdf

InterPro 24.0