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InterPro: IPR003702 Acetyl-CoA hydrolase/transferase

Protein matches Help

UniProtKB

Matches:

1018 proteins

Overview:	sorted by AC,	sorted by name,	of known structure,	proteins with splice variants
Detailed:	sorted by AC,	sorted by name,	of known structure	proteins with splice variants
Table:	For all matching proteins,	of known structure
Architectures
Accession List
Matches in BioMart

Accession

IPR003702 ActCoA_hydro

Type

Family

Signatures Help

Database	ID	Name	Proteins
Pfam	PF02550	AcetylCoA_hydro	846
PANTHER	PTHR21432	ActCoA_hydro	1013
Signatures in BioMart

InterPro Relationships Help

Children

IPR017821 Succinate CoA transferase

GO Term annotation Help

Process

GO:0006084 acetyl-CoA metabolic process

Function

GO:0003824 catalytic activity

InterPro annotation

Entry Details in BioMart

Abstract

This family contains several enzymes which take part in pathways involving acetyl-CoA. Acetyl-CoA hydrolase EC:3.1.2.1 from yeast catalyses the formation of acetate from acetyl-CoA, CoA transferase (CAT1) EC:2.8.3 produces succinyl-CoA, and acetate-CoA transferase EC:2.8.3.8 utilises acyl-CoA and acetate to form acetyl-CoA.

Structural links Help

PDB - click here

SCOP: c.124.1.2

CATH: 3.40.1080.10

Database links Help

PANDIT: PF02550

Blocks: IPB003702

Pfam Clan: CL0246.4

Taxonomic coverage Help

Overlapping InterPro entries Help

IPR003702

Numbers of overlapping proteins

Average numbers of overlapping amino acids

Example proteins Help

P15937 Acetyl-CoA hydrolase

P32316 Acetyl-CoA hydrolase

P38942 4-hydroxybutyrate coenzyme A transferase

Q54K91 Acetyl-CoA hydrolase

More proteins

Example Proteins Key

InterPro entry accession number/name and structure databases		Colour code
IPR003702	Acetyl-CoA hydrolase/transferase
	SWISS-MODEL
	ModBase

Publications Help

Additional Reading Open in usermanual
	Van Dyck L, Purnelle B, Skala J, Goffeau A. An 11.4 kb DNA segment on the left arm of yeast chromosome II carries the carboxypeptidase Y sorting gene PEP1, as well as ACH1, FUS3 and a putative ARS. Yeast 8 1992 769-76 [PubMed: 1441754] http://dx.doi.org/10.1002/yea.320080910
	Sohling B, Gottschalk G. Molecular analysis of the anaerobic succinate degradation pathway in Clostridium kluyveri. J. Bacteriol. 178 1996 871-80 [PubMed: 8550525] http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=EBI&pubmedid=8550525

InterPro 23.1