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InterPro: IPR003202 DNA polymerase processivity factor (UL42)

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UniProtKB

Matches:

39 proteins

Overview:	sorted by AC,	sorted by name,	of known structure,	proteins with splice variants
Detailed:	sorted by AC,	sorted by name,	of known structure	proteins with splice variants
Table:	For all matching proteins,	of known structure
Architectures
Accession List
Matches in BioMart

Accession

IPR003202 UL42

Type

Family

Signatures Help

Database	ID	Name	Proteins
Pfam	PF02282	Herpes_UL42	39
Signatures in BioMart

GO Term annotation Help

Process

GO:0006260 DNA replication

Function

GO:0003677 DNA binding

InterPro annotation

Entry Details in BioMart

Abstract

The DNA polymerase processivity factor (UL42) of Human herpesvirus 1 (HHV-1) forms a heterodimer with UL30 to create the viral DNA polymerase complex. UL42 functions to increase the processivity of polymerisation and makes little contribution to the catalytic activity of the polymerase.

Structural links Help

PDB - click here

SCOP: d.131.1.2

CATH: 3.70.10.10

Database links Help

PANDIT: PF02282

Blocks: IPB003202

Pfam Clan: CL0060.8

Taxonomic coverage Help

Example proteins Help

P10226 DNA polymerase processivity factor

More proteins

Example Proteins Key

InterPro entry accession number/name and structure databases		Colour code
IPR003202	DNA polymerase processivity factor (UL42)
	PDB Chain
	ModBase
	SCOP Domain
	CATH Domain

Publications Help

Additional Reading Open in usermanual
	Gottlieb J, Marcy AI, Coen DM, Challberg MD. The herpes simplex virus type 1 UL42 gene product: a subunit of DNA polymerase that functions to increase processivity. J. Virol. 64 1990 5976-87 [PubMed: 2173776] http://www.pubmedcentral.nih.gov/picrender.fcgi?tool=EBI&pubmedid=2173776&action=stream&blobtype=pdf
	Zuccola HJ, Filman DJ, Coen DM, Hogle JM. The crystal structure of an unusual processivity factor, herpes simplex virus UL42, bound to the C terminus of its cognate polymerase. Mol. Cell 5 2000 267-78 [PubMed: 10882068] http://dx.doi.org/10.1016/S1097-2765(00)80422-0

InterPro 24.0