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InterPro: IPR002860 BNR repeat

Protein matches Help

UniProtKB

Matches:

526 proteins

Overview:	sorted by AC,	sorted by name,	of known structure,	proteins with splice variants
Detailed:	sorted by AC,	sorted by name,	of known structure	proteins with splice variants
Table:	For all matching proteins,	of known structure
Architectures
Accession List
Matches in BioMart

Accession

IPR002860 BNR

Type

Repeat

Signatures Help

Database	ID	Name	Proteins
Pfam	PF02012	BNR	526
Signatures in BioMart

InterPro Relationships Help

Found in

IPR011040 Neuraminidase

InterPro annotation

Entry Details in BioMart

Abstract

Members of this family contain multiple BNR (bacterial neuraminidase repeat) repeats or Asp-boxes. The repeats are short, however the repeats are never found closer than 40 residues together suggesting that the repeat is structurally longer. These repeats are found in a variety of non-homologous proteins, including bacterial ribonucleases, sulphite oxidases, reelin, netrins, sialidases, neuraminidases, some lipoprotein receptors, and a variety of glycosyl hydrolases [1].

Structural links Help

PDB - click here

SCOP: b.68.1.1

CATH: 2.120.10.10

Database links Help

PANDIT: PF02012

Blocks: IPB002860

Taxonomic coverage Help

Example proteins Help

P29768 Sialidase

P32319 Vacuolar protein sorting/targeting protein PEP1

Q3MC08 Ycf48-like protein

Q64393 Sialidase-2

More proteins

Example Proteins Key

InterPro entry accession number/name and structure databases		Colour code
IPR002860	BNR repeat
IPR016705	Photosystem II stability/assembly factor, HCF136
IPR008377	Trypanosome sialidase
IPR011040	Neuraminidase
IPR006581	VPS10
	SWISS-MODEL
	PDB Chain
	ModBase
	SCOP Domain
	CATH Domain

Publications Open in usermanual
1.	Copley RR, Russell RB, Ponting CP. Sialidase-like Asp-boxes: sequence-similar structures within different protein folds. Protein Sci. 10 285-92 2001 [PubMed: 11266614] http://dx.doi.org/10.1110/ps.31901

Additional Reading Open in usermanual
	Crennell SJ, Garman EF, Philippon C, Vasella A, Laver WG, Vimr ER, Taylor GL. The structures of Salmonella typhimurium LT2 neuraminidase and its complexes with three inhibitors at high resolution. J. Mol. Biol. 259 1996 264-80 [PubMed: 8656428] http://dx.doi.org/10.1006/jmbi.1996.0318
	Roggentin P, Rothe B, Kaper JB, Galen J, Lawrisuk L, Vimr ER, Schauer R. Conserved sequences in bacterial and viral sialidases. Glycoconj. J. 6 1989 349-53 [PubMed: 2562507] http://dx.doi.org/10.1007/BF01047853

InterPro 23.1