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InterPro: IPR002844 Methylene-5,6,7,8-tetrahydromethanopterin dehydrogenase

UniProtKB

Matches:

33 proteins

Overview:	sorted by AC,	sorted by name,	of known structure,	proteins with splice variants
Detailed:	sorted by AC,	sorted by name,	of known structure	proteins with splice variants
Table:	For all matching proteins,	of known structure
Architectures
Accession List
Matches in BioMart

IPR002844 Methylene_DH

Type

Family

Signatures Help

Process

GO:0015948 methanogenesis
GO:0055114 oxidation reduction

Function

GO:0008901 ferredoxin hydrogenase activity

InterPro annotation

This archaeal enzyme family is involved in formation of methane from carbon dioxide EC:1.5.99.9. The enzyme requires coenzyme F420 [1].

SCOP: c.127.1.1

Enzyme: EC:1.5.99.9

PANDIT: PF01993

P94951 F420-dependent methylenetetrahydromethanopterin dehydrogenase

InterPro entry accession number/name and structure databases		Colour code
IPR002844	Methylene-5,6,7,8-tetrahydromethanopterin dehydrogenase
	PDB Chain
	SCOP Domain

Publications Open in usermanual
1.	Mukhopadhyay B, Purwantini E, Pihl TD, Reeve JN, Daniels L. Cloning, sequencing, and transcriptional analysis of the coenzyme F420-dependent methylene-5,6,7,8-tetrahydromethanopterin dehydrogenase gene from Methanobacterium thermoautotrophicum strain Marburg and functional expression in Escherichia coli. J. Biol. Chem. 270 2827-32 1995 [PubMed: 7852356] http://dx.doi.org/10.1074/jbc.270.6.2827

Additional Reading Open in usermanual
	Warkentin E, Hagemeier CH, Shima S, Thauer RK, Ermler U. The structure of F420-dependent methylenetetrahydromethanopterin dehydrogenase: a crystallographic 'superstructure' of the selenomethionine-labelled protein crystal structure. Acta Crystallogr. D Biol. Crystallogr. 61 2005 198-202 [PubMed: 15681872] http://dx.doi.org/10.1107/S0907444904030732
	Hagemeier CH, Shima S, Thauer RK, Bourenkov G, Bartunik HD, Ermler U. Coenzyme F420-dependent methylenetetrahydromethanopterin dehydrogenase (Mtd) from Methanopyrus kandleri: a methanogenic enzyme with an unusual quarternary structure. J. Mol. Biol. 332 2003 1047-57 [PubMed: 14499608] http://dx.doi.org/10.1016/S0022-2836(03)00949-5

InterPro 23.1