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InterPro: IPR002738 RNase P subunit p30

Protein matches Help

UniProtKB

Matches:

211 proteins

Overview:	sorted by AC,	sorted by name,	of known structure,	proteins with splice variants
Detailed:	sorted by AC,	sorted by name,	of known structure	proteins with splice variants
Table:	For all matching proteins,	of known structure
Architectures
Accession List
Matches in BioMart

Accession

IPR002738 RNase_P_p30

Type

Family

Signatures Help

Database	ID	Name	Proteins
Pfam	PF01876	RNase_P_p30	198
PANTHER	PTHR13031	RNase_P_p30	154
Signatures in BioMart

InterPro Relationships Help

Contains

IPR016195 Polymerase/histidinol phosphatase-like

GO Term annotation Help

Process

GO:0008033 tRNA processing

Function

GO:0004540 ribonuclease activity

InterPro annotation

Entry Details in BioMart

Abstract

Members of this protein family are part of the ribonuclease P complex (EC:3.1.26.5 ) that takes part in endonucleolytic cleavage of RNA, removing 5'-extra-nucleotide from tRNA precursor. This process is essential for tRNA processing.

Structural links Help

PDB - click here

SCOP: c.6.3.2

CATH: 3.20.20.140

Database links Help

Enzyme: EC:3.1.26.5

PANDIT: PF01876

Blocks: IPB002738

Taxonomic coverage Help

Overlapping InterPro entries Help

IPR002738

Numbers of overlapping proteins

Average numbers of overlapping amino acids

Example proteins Help

O59543 Ribonuclease P protein component 3

O88796 Ribonuclease P protein subunit p30

P38786 Ribonuclease P/MRP protein subunit RPP1

P78346 Ribonuclease P protein subunit p30

Q3SZ21 Ribonuclease P protein subunit p30

More proteins

Example Proteins Key

InterPro entry accession number/name and structure databases		Colour code
IPR002738	RNase P subunit p30
IPR016195	Polymerase/histidinol phosphatase-like
	SWISS-MODEL
	PDB Chain
	ModBase
	CATH Domain
	SCOP Domain

Publications Help

Additional Reading Open in usermanual
	Dlakic M. 3D models of yeast RNase P/MRP proteins Rpp1p and Pop3p. RNA 11 2005 123-7 [PubMed: 15613537] http://dx.doi.org/10.1261/rna.7128905
	Takagi H, Watanabe M, Kakuta Y, Kamachi R, Numata T, Tanaka I, Kimura M. Crystal structure of the ribonuclease P protein Ph1877p from hyperthermophilic archaeon Pyrococcus horikoshii OT3. Biochem. Biophys. Res. Commun. 319 2004 787-94 [PubMed: 15184052] http://dx.doi.org/10.1016/j.bbrc.2004.05.055
	Kawano S, Nakashima T, Kakuta Y, Tanaka I, Kimura M. Crystal structure of protein Ph1481p in complex with protein Ph1877p of archaeal RNase P from Pyrococcus horikoshii OT3: implication of dimer formation of the holoenzyme. J. Mol. Biol. 357 2006 583-91 [PubMed: 16430919] http://dx.doi.org/10.1016/j.jmb.2005.12.086
	Eder PS, Kekuda R, Stolc V, Altman S. Characterization of two scleroderma autoimmune antigens that copurify with human ribonuclease P. Proc. Natl. Acad. Sci. U.S.A. 94 1997 1101-6 [PubMed: 9037013] http://dx.doi.org/10.1073/pnas.94.4.1101

InterPro 23.1