EBI Databases InterPro	Search Open in usermanual InterPro:
Jump to: InterProScan Databases Documentation FTP site Help Click on the icon for context sensitive help from the user manual. Advanced search

InterPro: IPR002686 Transposase IS200-like

Protein matches Help

UniProtKB

Matches:

1437 proteins

Overview:	sorted by AC,	sorted by name,	of known structure,	proteins with splice variants
Detailed:	sorted by AC,	sorted by name,	of known structure	proteins with splice variants
Table:	For all matching proteins,	of known structure
Architectures
Accession List
Matches in BioMart

Accession

IPR002686 Transposase_17

Type

Family

Signatures Help

Database	ID	Name	Proteins
Pfam	PF01797	Transposase_17	1437
Signatures in BioMart

GO Term annotation Help

Process

GO:0006313 transposition, DNA-mediated

Function

GO:0003677 DNA binding
GO:0004803 transposase activity

InterPro annotation

Entry Details in BioMart

Abstract

Transposases are needed for efficient transposition of the insertion sequence or transposon DNA. This family includes transposases for IS200 from Escherichia coli [1].

More information about these proteins can be found at Protein of the Month: Transposase [2].

Structural links Help

PDB - click here

SCOP: d.58.57.1

CATH: 3.30.70.1290

Database links Help

PANDIT: PF01797

Taxonomic coverage Help

Example proteins Help

P59696 Transposase for insertion sequence element IS200

More proteins

Example Proteins Key

InterPro entry accession number/name and structure databases		Colour code
IPR002686	Transposase IS200-like
	SWISS-MODEL

Publications Open in usermanual
1.	Beuzon CR, Marques S, Casadesus J. Repression of IS200 transposase synthesis by RNA secondary structures. Nucleic Acids Res. 27 3690-5 1999 [PubMed: 10471738] http://dx.doi.org/10.1093/nar/27.18.3690
2.	McDowall J. Protein of the Month ? Transposase. 2006

Additional Reading Open in usermanual
	Brynestad S, Synstad B, Granum PE. The Clostridium perfringens enterotoxin gene is on a transposable element in type A human food poisoning strains. Microbiology (Reading, Engl.) 143 ( Pt 7) 1997 2109-15 [PubMed: 9245800]
	Ronning DR, Guynet C, Ton-Hoang B, Perez ZN, Ghirlando R, Chandler M, Dyda F. Active site sharing and subterminal hairpin recognition in a new class of DNA transposases. Mol. Cell 20 2005 143-54 [PubMed: 16209952] http://dx.doi.org/10.1016/j.molcel.2005.07.026
	Barabas O, Ronning DR, Guynet C, Hickman AB, Ton-Hoang B, Chandler M, Dyda F. Mechanism of IS200/IS605 family DNA transposases: activation and transposon-directed target site selection. Cell 132 2008 208-20 [PubMed: 18243097] http://dx.doi.org/10.1016/j.cell.2007.12.029
	Lee HH, Yoon JY, Kim HS, Kang JY, Kim KH, Kim DJ, Ha JY, Mikami B, Yoon HJ, Suh SW. Crystal structure of a metal ion-bound IS200 transposase. J. Biol. Chem. 281 2006 4261-6 [PubMed: 16340015] http://dx.doi.org/10.1074/jbc.M511567200

InterPro 23.1