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InterPro: IPR002505 Phosphate acetyl/butaryl transferase

Protein matches Help

UniProtKB

Matches:

2627 proteins

Overview:	sorted by AC,	sorted by name,	of known structure,	proteins with splice variants
Detailed:	sorted by AC,	sorted by name,	of known structure	proteins with splice variants
Table:	For all matching proteins,	of known structure
Architectures
Accession List
Matches in BioMart

Accession

IPR002505 PTA_PTB

Type

Domain

Signatures Help

Database	ID	Name	Proteins
Pfam	PF01515	PTA_PTB	2627
Signatures in BioMart

InterPro Relationships Help

Children

IPR004614 Phosphate acetyltransferase

Found in

IPR012188 Malic enzyme, phosphate acetyl/butaryl transferase
IPR014079 Phosphate butyryltransferase
IPR014081 Branched-chain phosphotransacylase

GO Term annotation Help

Process

GO:0008152 metabolic process

Function

GO:0008415 acyltransferase activity

InterPro annotation

Entry Details in BioMart

Abstract

This entry contains both phosphate acetyltransferase EC:2.3.1.8:

Acetyl-CoA + phosphate = CoA + acetyl phosphate

and phosphate butaryltransferase EC:2.3.1.19:

Butanoyl-CoA + phosphate = CoA + butanoyl phosphate

These enzymes catalyse the transfer of an acetyl or butaryl group to orthophosphate.

Structural links Help

PDB - click here

SCOP: c.77.1.5

Database links Help

Enzyme: EC:2.3.1

PANDIT: PF01515

Blocks: IPB002505

Pfam Clan: CL0270.3

Taxonomic coverage Help

Overlapping InterPro entries Help

IPR002505

Numbers of overlapping proteins

Average numbers of overlapping amino acids

Example proteins Help

P38503 Phosphate acetyltransferase

P39646 Phosphate acetyltransferase

P73662 Phosphate acetyltransferase

More proteins

Example Proteins Key

InterPro entry accession number/name and structure databases		Colour code
IPR004614	Phosphate acetyltransferase
IPR010766	DRTGG
IPR002505	Phosphate acetyl/butaryl transferase
IPR016475	Phosphate acetyltransferase, bacteria
IPR012147	Phosphate acetyl/butyryltransferase
	SWISS-MODEL
	PDB Chain
	ModBase
	SCOP Domain

Publications Help

Additional Reading Open in usermanual
	Lawrence SH, Luther KB, Schindelin H, Ferry JG. Structural and functional studies suggest a catalytic mechanism for the phosphotransacetylase from Methanosarcina thermophila. J. Bacteriol. 188 2006 1143-54 [PubMed: 16428418] http://dx.doi.org/10.1128/JB.188.3.1143-1154.2006
	Xu QS, Shin DH, Pufan R, Yokota H, Kim R, Kim SH. Crystal structure of a phosphotransacetylase from Streptococcus pyogenes. Proteins 55 2004 479-81 [PubMed: 15048838] http://dx.doi.org/10.1002/prot.20039
	Xu QS, Jancarik J, Lou Y, Kuznetsova K, Yakunin AF, Yokota H, Adams P, Kim R, Kim SH. Crystal structures of a phosphotransacetylase from Bacillus subtilis and its complex with acetyl phosphate. J. Struct. Funct. Genomics 6 2005 269-79 [PubMed: 16283428] http://dx.doi.org/10.1007/s10969-005-9001-9
	Iyer PP, Lawrence SH, Luther KB, Rajashankar KR, Yennawar HP, Ferry JG, Schindelin H. Crystal structure of phosphotransacetylase from the methanogenic archaeon Methanosarcina thermophila. Structure 12 2004 559-67 [PubMed: 15062079] http://dx.doi.org/10.1016/j.str.2004.03.007

InterPro 23.1