EBI Databases InterPro	Search Open in usermanual InterPro:
Jump to: InterProScan Databases Documentation FTP site Help Click on the icon for context sensitive help from the user manual. Advanced search

InterPro: IPR002482 Peptidoglycan-binding Lysin subgroup

Protein matches Help

UniProtKB

Matches:

7319 proteins

Overview:	sorted by AC,	sorted by name,	of known structure,	proteins with splice variants
Detailed:	sorted by AC,	sorted by name,	of known structure	proteins with splice variants
Table:	For all matching proteins,	of known structure
Architectures
Accession List
Matches in BioMart

Accession

IPR002482 Peptidoglycan-bd_Lysin_sg

Type

Domain

Signatures Help

Database	ID	Name	Proteins
SMART	SM00257	LysM	7319
Signatures in BioMart

InterPro Relationships Help

Parent

IPR018392 Peptidoglycan-binding lysin domain

Children

IPR014248 Spore coat assembly protein SafA

Found in

IPR014256 Sporulation stage VI, protein D

GO Term annotation Help

Process

GO:0016998 cell wall macromolecule catabolic process

InterPro annotation

Entry Details in BioMart

Abstract

This domain is about 40 residues long and is found in a variety of enzymes involved in bacterial cell wall degradation [1]. This domain may have a general peptidoglycan binding function.

Structural links Help

PDB - click here

SCOP: d.7.1.1

CATH: 3.10.350.10

Database links Help

PANDIT: PF01476

Blocks: IPB002482

Taxonomic coverage Help

Overlapping InterPro entries Help

IPR002482

Numbers of overlapping proteins

Average numbers of overlapping amino acids

Example proteins Help

O05495 Putative sporulation-specific glycosylase ydhD

O23006 LysM domain-containing GPI-anchored protein 2

Q4KMM3 Oxidation resistance protein 1

Q8H8C7 Chitin elicitor-binding protein

Q96S90 LysM and putative peptidoglycan-binding domain-containing protein 1

More proteins

Example Proteins Key

InterPro entry accession number/name and structure databases		Colour code
IPR013781	Glycoside hydrolase, subgroup, catalytic core
IPR002482	Peptidoglycan-binding Lysin subgroup
IPR018392	Peptidoglycan-binding lysin domain
IPR017853	Glycoside hydrolase, catalytic core
IPR011583	Chitinase II
IPR004182	GRAM
IPR006571	TLDc
IPR001223	Glycoside hydrolase, family 18, catalytic domain
	SWISS-MODEL
	PDB Chain
	ModBase

Publications Open in usermanual
1.	Joris B, Englebert S, Chu CP, Kariyama R, Daneo-Moore L, Shockman GD, Ghuysen JM. Modular design of the Enterococcus hirae muramidase-2 and Streptococcus faecalis autolysin. FEMS Microbiol. Lett. 70 257-64 1992 [PubMed: 1352512] http://dx.doi.org/10.1016/0378-1097(92)90707-U

Additional Reading Open in usermanual
	Bateman A, Bycroft M. The structure of a LysM domain from E. coli membrane-bound lytic murein transglycosylase D (MltD). J. Mol. Biol. 299 2000 1113-9 [PubMed: 10843862] http://dx.doi.org/10.1006/jmbi.2000.3778
	Birkeland NK. Cloning, molecular characterization, and expression of the genes encoding the lytic functions of lactococcal bacteriophage phi LC3: a dual lysis system of modular design. Can. J. Microbiol. 40 1994 658-65 [PubMed: 7922887]
	Bielnicki J, Devedjiev Y, Derewenda U, Dauter Z, Joachimiak A, Derewenda ZS. B. subtilis ykuD protein at 2.0 A resolution: insights into the structure and function of a novel, ubiquitous family of bacterial enzymes. Proteins 62 2006 144-51 [PubMed: 16287140] http://dx.doi.org/10.1002/prot.20702

InterPro 23.1