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InterPro: IPR000829 Diacylglycerol kinase, prokaryotic

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1202 proteins

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Detailed:	sorted by AC,	sorted by name,	of known structure	proteins with splice variants
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Accession List
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Accession

IPR000829 Diacylglycerol_kinase_prok

Type

Family

Signatures Help

Database	ID	Name	Proteins
Pfam	PF01219	DAGK_prokar	1202
PROSITE pattern	PS01069	DAGK_PROKAR	706
Signatures in BioMart

GO Term annotation Help

Process

GO:0008654 phospholipid biosynthetic process

Function

GO:0004143 diacylglycerol kinase activity

Component

GO:0016020 membrane

InterPro annotation

Entry Details in BioMart

Abstract

Diacylglycerol kinase (EC:2.7.1.107) (DAGK) is an enzyme that catalyses the formation of phosphatidic acid from diacylglycerol and ATP, an important step in phospholipid biosynthesis. In bacteria DAGK is very small (13 to 15 kD) membrane protein which seems to contain three transmembrane domains [1]. The best conserved region, is a stretch of 12 residues which are located in a cytoplasmic loop between the second and third transmembrane domains.

Database links Help

PDBe-motif: PS01069

Enzyme: EC:2.7.1.107

PROSITE doc: PDOC00820

PANDIT: PF01219

Blocks: IPB000829

Taxonomic coverage Help

Example proteins Help

P0ABN1 Diacylglycerol kinase

Q55143 Probable diacylglycerol kinase

More proteins

Example Proteins Key

InterPro entry accession number/name and structure databases		Colour code
IPR000829	Diacylglycerol kinase, prokaryotic
	PDB Chain

Publications Open in usermanual
1.	Smith RL, O'Toole JF, Maguire ME, Sanders CR 2nd. Membrane topology of Escherichia coli diacylglycerol kinase. J. Bacteriol. 176 5459-65 1994 [PubMed: 8071224] http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=EBI&pubmedid=8071224

InterPro 23.1