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InterPro: IPR000407 Nucleoside phosphatase GDA1/CD39

Protein matches Help

UniProtKB

Matches:

630 proteins

Overview:	sorted by AC,	sorted by name,	of known structure,	proteins with splice variants
Detailed:	sorted by AC,	sorted by name,	of known structure	proteins with splice variants
Table:	For all matching proteins,	of known structure
Architectures
Accession List
Matches in BioMart

Accession

IPR000407 GDA1_CD39_NTPase

Type

Family

Signatures Help

Database	ID	Name	Proteins
Pfam	PF01150	GDA1_CD39	608
PROSITE pattern	PS01238	GDA1_CD39_NTPASE	378
PANTHER	PTHR11782	GDA1_CD39_NTPase	611
Signatures in BioMart

InterPro Relationships Help

Children

IPR015605 Guanosine diphosphatase
IPR017227 Nucleoside-triphosphatase, alveolata

GO Term annotation Help

Function

GO:0016787 hydrolase activity

InterPro annotation

Entry Details in BioMart

Abstract

A number of nucleoside diphosphate and triphosphate hydrolases as well as some yet uncharacterised proteins have been found to belong to the same family [1, 2]. The uncharacterised proteins all seem to be membrane-bound.

CD molecules are leucocyte antigens on cell surfaces. CD antigens nomenclature is updated at Protein Reviews On The Web (http://mpr.nci.nih.gov/prow/).

Database links Help

PDBe-motif: PS01238

Enzyme: EC:3.6.1

PROSITE doc: PDOC00952

PANDIT: PF01150

Blocks: IPB000407

Pfam Clan: CL0108.12

Taxonomic coverage Help

Overlapping InterPro entries Help

IPR000407

Numbers of overlapping proteins

Average numbers of overlapping amino acids

Example proteins Help

O35795 Ectonucleoside triphosphate diphosphohydrolase 2

O55026 Ectonucleoside triphosphate diphosphohydrolase 2

O75354 Ectonucleoside triphosphate diphosphohydrolase 6

P32621 Guanosine-diphosphatase

Q18411 Nucleoside-triphosphatase ntp-1

More proteins

Example Proteins Key

InterPro entry accession number/name and structure databases		Colour code
IPR000407	Nucleoside phosphatase GDA1/CD39
IPR015605	Guanosine diphosphatase
	SWISS-MODEL
	PDB Chain
	ModBase

Publications Open in usermanual
1.	Handa M, Guidotti G. Purification and cloning of a soluble ATP-diphosphohydrolase (apyrase) from potato tubers (Solanum tuberosum). Biochem. Biophys. Res. Commun. 218 916-23 1996 [PubMed: 8579614] http://dx.doi.org/10.1006/bbrc.1996.0162
2.	Vasconcelos EG, Ferreira ST, Carvalho TM, Souza W, Kettlun AM, Mancilla M, Valenzuela MA, Verjovski-Almeida S. Partial purification and immunohistochemical localization of ATP diphosphohydrolase from Schistosoma mansoni. Immunological cross-reactivities with potato apyrase and Toxoplasma gondii nucleoside triphosphate hydrolase. J. Biol. Chem. 271 22139-45 1996 [PubMed: 8703025] http://dx.doi.org/10.1074/jbc.271.36.22139

InterPro 23.1