InterPro: protein sequence analysis & classification

InterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites. We combine protein signatures from a number of member databases into a single searchable resource, capitalising on their individual strengths to produce a powerful integrated database and diagnostic tool. Read more about InterPro

Analyse your protein sequence


About InterPro: core concepts, update frequency, how to cite, team and consortium members.

FAQs: what are entry types and why are they important, interpreting results, downloading InterPro?

Web services documentation


NAR publication cover InterPro in 2017 — beyond protein family and domain annotations
Our latest paper describing new developments on the InterPro website (Nucleic Acids Research, Jan 2017).
HTML | PDF (2.4Mb) | All publications

Tools InterProScan

InterProScan logoInterProScan is a sequence analysis application (nucleotide and protein sequences) that combines different protein signature recognition methods into one resource.
More about InterProScan

Tools IDA

IDA domain architecture logoThe InterPro Domain Architecture (IDA) tool allows you to search the InterPro database with a particular set of domains, and returns all of the domain architectures and associated proteins that match the query.
Search IDAs

InterPro 67.0
1st March 2018
Features include:
  • The addition of 1139 InterPro entries.
  • An update to CATH-Gene3D (4.2.0).
  • Integration of 1362 new methods from the CATH-Gene3D (853), CDD (238), SUPERFAMILY (47), PANTHER (217), Pfam (3) and SFLD (4) databases.