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InterPro protein sequence analysis & classification

InterPro is an integrated database of predictive protein signatures used for the classification and automatic annotation of proteins and genomes. InterPro classifies sequences at superfamily, family and subfamily levels, predicting the occurrence of functional domains, repeats and important sites. InterPro adds in-depth annotation, including GO terms, to the protein signatures.

Current release: 35.0 15 December 2011 (see Release Notes for further details)



Do a sequence search of InterPro, via InterProScan

Extract large datasets by querying our BioMart BioMart Logo

You can access our data programmatically, via Web Services

Use the updated InterProScan Web Service


If you have any questions or feedback please contact us.

InterPro User Questionnaire

As part of our efforts to improve the services offered as part of InterPro, we would appreciate your feedback.

To this end, we would be extremely grateful if you could complete the short InterPro User Survey

This questionnaire focuses on your use of InterProScan and the InterPro BioMart, with a couple of more general questions about InterPro and the features that you would like to see in place in the future.

UniProt database consists of protein sequence entries. PROSITE is a database of protein families and domains. Pfam is a large collection of multiple sequence alignments and
            hidden Markov models covering many common protein domains. PRINTS is a compendium of protein fingerprints. ProDom protein domain database consists of an automatic compilation of homologous domains SMART allows the identification and annotation of genetically mobile domains TIGRFAMs is a collection of protein families. HAMAP PANTHER HMMs define protein families, and subfamilies modelled on the divergence of function PIRSF is a classification system based on evolutionary relationship of whole proteins. SUPERFAMILY is a library of profile hidden Markov models that represent all proteins of known structure, based on SCOP. Gene3D HMMs extended predictions of CATH protein structures Protein Databank in Europe SWISS-MODEL is a fully automated protein structure homology-modelling server. The purpose of this server is to make Protein Modelling accessible to all biochemists and molecular biologists World Wide. MODBASE models are generated by the fully automated homology-modelling pipeline MODPIPE.
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InterPro 35.0