EC 1.1.1.1 - Alcohol dehydrogenase

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ENZYME: 1.1.1.1


ID   1.1.1.1
DE   Alcohol dehydrogenase.
AN   Aldehyde reductase.
CA   (1) A primary alcohol + NAD(+) = an aldehyde + NADH.
CA   (2) A secondary alcohol + NAD(+) = a ketone + NADH.
CF   Zn(2+) or Fe cation.
CC   -!- Acts on primary or secondary alcohols or hemi-acetals with very broad
CC       specificity; however the enzyme oxidizes methanol much more poorly
CC       than ethanol.
CC   -!- The animal, but not the yeast, enzyme acts also on cyclic secondary
CC       alcohols.
PR   PROSITE; PDOC00058;
PR   PROSITE; PDOC00059;
PR   PROSITE; PDOC00060;
DR   P07327    , ADH1A_HUMAN;  P28469    , ADH1A_MACMU;  Q5RBP7    , ADH1A_PONAB;
DR   P25405    , ADH1A_SAAHA;  P00325    , ADH1B_HUMAN;  Q5R1W2    , ADH1B_PANTR;
DR   P14139    , ADH1B_PAPHA;  P25406    , ADH1B_SAAHA;  P00327    , ADH1E_HORSE;
DR   P00326    , ADH1G_HUMAN;  O97959    , ADH1G_PAPHA;  P00328    , ADH1S_HORSE;
DR   P80222    , ADH1_ALLMI ;  P30350    , ADH1_ANAPL ;  P49645    , ADH1_APTAU ;
DR   P06525    , ADH1_ARATH ;  P41747    , ADH1_ASPFN ;  Q17334    , ADH1_CAEEL ;
DR   P43067    , ADH1_CANAX ;  P85440    , ADH1_CATRO ;  P48814    , ADH1_CERCA ;
DR   Q70UN9    , ADH1_CERCO ;  P23991    , ADH1_CHICK ;  P86883    , ADH1_COLLI ;
DR   P19631    , ADH1_COTJA ;  P23236    , ADH1_DROHY ;  P48586    , ADH1_DROMN ;
DR   P09370    , ADH1_DROMO ;  P22246    , ADH1_DROMT ;  P07161    , ADH1_DROMU ;
DR   P12854    , ADH1_DRONA ;  P08843    , ADH1_EMENI ;  P26325    , ADH1_GADMC ;
DR   Q9Z2M2    , ADH1_GEOAT ;  Q64413    , ADH1_GEOBU ;  Q64415    , ADH1_GEOKN ;
DR   P12311    , ADH1_GEOSE ;  P05336    , ADH1_HORVU ;  P20369    , ADH1_KLULA ;
DR   Q07288    , ADH1_KLUMA ;  P00333    , ADH1_MAIZE ;  P86885    , ADH1_MESAU ;
DR   P00329    , ADH1_MOUSE ;  P80512    , ADH1_NAJNA ;  Q9P6C8    , ADH1_NEUCR ;
DR   Q75ZX4    , ADH1_ORYSI ;  Q2R8Z5    , ADH1_ORYSJ ;  P12886    , ADH1_PEA   ;
DR   P22797    , ADH1_PELPE ;  P14219    , ADH1_PENAM ;  P41680    , ADH1_PERMA ;
DR   P25141    , ADH1_PETHY ;  O00097    , ADH1_PICST ;  Q03505    , ADH1_RABIT ;
DR   P06757    , ADH1_RAT   ;  P14673    , ADH1_SOLTU ;  P80338    , ADH1_STRCA ;
DR   P13603    , ADH1_TRIRP ;  P00330    , ADH1_YEAST ;  Q07264    , ADH1_ZEALU ;
DR   P20368    , ADH1_ZYMMO ;  O45687    , ADH2_CAEEL ;  O94038    , ADH2_CANAL ;
DR   P48815    , ADH2_CERCA ;  Q70UP5    , ADH2_CERCO ;  Q70UP6    , ADH2_CERRO ;
DR   P27581    , ADH2_DROAR ;  P25720    , ADH2_DROBU ;  P23237    , ADH2_DROHY ;
DR   P48587    , ADH2_DROMN ;  P09369    , ADH2_DROMO ;  P07160    , ADH2_DROMU ;
DR   P24267    , ADH2_DROWH ;  P37686    , ADH2_ECOLI ;  P54202    , ADH2_EMENI ;
DR   Q24803    , ADH2_ENTHI ;  P42327    , ADH2_GEOSE ;  P10847    , ADH2_HORVU ;
DR   P49383    , ADH2_KLULA ;  Q9P4C2    , ADH2_KLUMA ;  P04707    , ADH2_MAIZE ;
DR   Q4R1E8    , ADH2_ORYSI ;  Q0ITW7    , ADH2_ORYSJ ;  O13309    , ADH2_PICST ;
DR   P28032    , ADH2_SOLLC ;  P14674    , ADH2_SOLTU ;  F2Z678    , ADH2_YARLI ;
DR   P00331    , ADH2_YEAST ;  F8DVL8    , ADH2_ZYMMA ;  P0DJA2    , ADH2_ZYMMO ;
DR   P07754    , ADH3_EMENI ;  P42328    , ADH3_GEOSE ;  P10848    , ADH3_HORVU ;
DR   P49384    , ADH3_KLULA ;  P14675    , ADH3_SOLTU ;  P07246    , ADH3_YEAST ;
DR   P08319    , ADH4_HUMAN ;  P49385    , ADH4_KLULA ;  Q9QYY9    , ADH4_MOUSE ;
DR   Q64563    , ADH4_RAT   ;  Q09669    , ADH4_SCHPO ;  P80468    , ADH4_STRCA ;
DR   A6ZTT5    , ADH4_YEAS7 ;  P10127    , ADH4_YEAST ;  Q6XQ67    , ADH5_SACPS ;
DR   P38113    , ADH5_YEAST ;  P28332    , ADH6_HUMAN ;  P41681    , ADH6_PERMA ;
DR   Q5R7Z8    , ADH6_PONAB ;  Q5XI95    , ADH6_RAT   ;  P40394    , ADH7_HUMAN ;
DR   Q64437    , ADH7_MOUSE ;  P41682    , ADH7_RAT   ;  P9WQC0    , ADHA_MYCTO ;
DR   P9WQC1    , ADHA_MYCTU ;  O31186    , ADHA_RHIME ;  Q7U1B9    , ADHB_MYCBO ;
DR   P9WQC6    , ADHB_MYCTO ;  P9WQC7    , ADHB_MYCTU ;  P9WQB8    , ADHD_MYCTO ;
DR   P9WQB9    , ADHD_MYCTU ;  P33744    , ADHE_CLOAB ;  P0A9Q8    , ADHE_ECO57 ;
DR   P0A9Q7    , ADHE_ECOLI ;  P81600    , ADHH_GADMO ;  P72324    , ADHI_RHOS4 ;
DR   Q9SK86    , ADHL1_ARATH;  Q9SK87    , ADHL2_ARATH;  A1L4Y2    , ADHL3_ARATH;
DR   Q8VZ49    , ADHL4_ARATH;  Q0V7W6    , ADHL5_ARATH;  Q8LEB2    , ADHL6_ARATH;
DR   Q9FH04    , ADHL7_ARATH;  P81601    , ADHL_GADMO ;  P39451    , ADHP_ECOLI ;
DR   O46649    , ADHP_RABIT ;  O46650    , ADHQ_RABIT ;  Q96533    , ADHX_ARATH ;
DR   Q3ZC42    , ADHX_BOVIN ;  Q17335    , ADHX_CAEEL ;  Q54TC2    , ADHX_DICDI ;
DR   P46415    , ADHX_DROME ;  P19854    , ADHX_HORSE ;  P11766    , ADHX_HUMAN ;
DR   P93629    , ADHX_MAIZE ;  P28474    , ADHX_MOUSE ;  P80360    , ADHX_MYXGL ;
DR   P81431    , ADHX_OCTVU ;  A2XAZ3    , ADHX_ORYSI ;  Q0DWH1    , ADHX_ORYSJ ;
DR   P80572    , ADHX_PEA   ;  O19053    , ADHX_RABIT ;  P12711    , ADHX_RAT   ;
DR   P80467    , ADHX_SAAHA ;  P86884    , ADHX_SCYCA ;  P79896    , ADHX_SPAAU ;
DR   Q9NAR7    , ADH_BACOL  ;  P14940    , ADH_CUPNE  ;  Q0KDL6    , ADH_CUPNH  ;
DR   Q00669    , ADH_DROAD  ;  P21518    , ADH_DROAF  ;  P25139    , ADH_DROAM  ;
DR   Q50L96    , ADH_DROAN  ;  P48584    , ADH_DROBO  ;  P22245    , ADH_DRODI  ;
DR   Q9NG42    , ADH_DROEQ  ;  P28483    , ADH_DROER  ;  P48585    , ADH_DROFL  ;
DR   P51551    , ADH_DROGR  ;  Q09009    , ADH_DROGU  ;  P51549    , ADH_DROHA  ;
DR   P21898    , ADH_DROHE  ;  Q07588    , ADH_DROIM  ;  Q9NG40    , ADH_DROIN  ;
DR   Q27404    , ADH_DROLA  ;  P10807    , ADH_DROLE  ;  P07162    , ADH_DROMA  ;
DR   Q09010    , ADH_DROMD  ;  P00334    , ADH_DROME  ;  Q00671    , ADH_DROMM  ;
DR   P25721    , ADH_DROMY  ;  Q00672    , ADH_DRONI  ;  P07159    , ADH_DROOR  ;
DR   P84328    , ADH_DROPB  ;  P37473    , ADH_DROPE  ;  P23361    , ADH_DROPI  ;
DR   P23277    , ADH_DROPL  ;  Q6LCE4    , ADH_DROPS  ;  Q9U8S9    , ADH_DROPU  ;
DR   Q9GN94    , ADH_DROSE  ;  Q24641    , ADH_DROSI  ;  P23278    , ADH_DROSL  ;
DR   Q03384    , ADH_DROSU  ;  P28484    , ADH_DROTE  ;  P51550    , ADH_DROTS  ;
DR   B4M8Y0    , ADH_DROVI  ;  Q05114    , ADH_DROWI  ;  P26719    , ADH_DROYA  ;
DR   P17648    , ADH_FRAAN  ;  P48977    , ADH_MALDO  ;  P81786    , ADH_MORSE  ;
DR   P9WQC2    , ADH_MYCTO  ;  P9WQC3    , ADH_MYCTU  ;  P25988    , ADH_SCAAL  ;
DR   Q00670    , ADH_SCACA  ;  P00332    , ADH_SCHPO  ;  Q2FJ31    , ADH_STAA3  ;
DR   Q2G0G1    , ADH_STAA8  ;  Q2YSX0    , ADH_STAAB  ;  Q5HI63    , ADH_STAAC  ;
DR   Q99W07    , ADH_STAAM  ;  Q7A742    , ADH_STAAN  ;  Q6GJ63    , ADH_STAAR  ;
DR   Q6GBM4    , ADH_STAAS  ;  Q8NXU1    , ADH_STAAW  ;  Q5HRD6    , ADH_STAEQ  ;
DR   Q8CQ56    , ADH_STAES  ;  Q4J781    , ADH_SULAC  ;  P39462    , ADH_SULSO  ;
DR   P50381    , ADH_SULSR  ;  Q96XE0    , ADH_SULTO  ;  P51552    , ADH_ZAPTU  ;
DR   Q5AR48    , ASQE_EMENI ;  A5JYX5    , DHS3_CAEEL ;  P32771    , FADH_YEAST ;
DR   A7ZIA4    , FRMA_ECO24 ;  Q8X5J4    , FRMA_ECO57 ;  A7ZX04    , FRMA_ECOHS ;
DR   A1A835    , FRMA_ECOK1 ;  Q0TKS7    , FRMA_ECOL5 ;  Q8FKG1    , FRMA_ECOL6 ;
DR   B1J085    , FRMA_ECOLC ;  P25437    , FRMA_ECOLI ;  B1LIP1    , FRMA_ECOSM ;
DR   Q1RFI7    , FRMA_ECOUT ;  P44557    , FRMA_HAEIN ;  P39450    , FRMA_PHODP ;
DR   Q3Z550    , FRMA_SHISS ;  P73138    , FRMA_SYNY3 ;  P71017    , GBSB_BACSU ;
DR   N4WE73    , OXI1_COCH4 ;  A1CFL1    , PATD_ASPCL ;  N4WE43    , RED2_COCH4 ;
DR   N4WW42    , RED3_COCH4 ;  P33010    , TERPD_PSESP;  O07737    , Y1895_MYCTU;
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