EC 6.3.4.13 - Phosphoribosylamine—glycine ligase

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IntEnz Enzyme Nomenclature
EC 6.3.4.13

Names

Accepted name:
phosphoribosylamine—glycine ligase
Other names:
2-amino-N-ribosylacetamide 5'-phosphate kinosynthase
5'-phosphoribosylglycinamide synthetase
GAR
glycinamide ribonucleotide synthetase
glycineamide ribonucleotide synthetase
phosphoribosylglycinamide synthetase
phosphoribosylglycineamide synthetase
GARS
GAR synthetase
Systematic name:
5-phospho-D-ribosylamine:glycine ligase (ADP-forming)

Reaction

Comments:

Formerly EC 6.3.1.3.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , DIAGRAM , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Protein domains and families: PROSITE:PDOC00164 , PROSITE:PDOC50975
Structural data: CSA , EC2PDB
Gene Ontology: GO:0004637
CAS Registry Number: 9032-01-3
UniProtKB/Swiss-Prot: (116) [show] [UniProt]

References

  1. Goldthwait, D.A., Peabody, R.A. and Greenberg, G.R.
    On the mechanism of synthesis of glycinamide ribotide and its formyl derivative.
    J. Biol. Chem. 221: 569-577 (1956). [PMID: 13357451]
  2. Hartman, S.C. and Buchanan, J.M.
    Biosynthesis of the purines. XXII. 2-Amino-N-ribosylacetamide-5'-phosphate kinosynthase.
    J. Biol. Chem. 233: 456-461 (1958). [PMID: 13563520]

[EC 6.3.4.13 created 1961 as EC 6.3.1.3, transferred 1972 to EC 6.3.4.13, modified 2000]