EC 5.4.99.7 - Lanosterol synthase

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IntEnz Enzyme Nomenclature
EC 5.4.99.7

Names

Accepted name:
lanosterol synthase
Other names:
2,3-epoxysqualene lanosterol cyclase
2,3-oxidosqualene cyclase
2,3-oxidosqualene sterol cyclase
2,3-oxidosqualene—lanosterol cyclase
lanosterol 2,3-oxidosqualene cyclase
oxidosqualene cyclase
oxidosqualene—lanosterol cyclase
squalene 2,3-epoxide:lanosterol cyclase
squalene epoxidase-cyclase
squalene-2,3-oxide-lanosterol cyclase
2,3-epoxysqualene--lanosterol cyclase
(S)-2,3-epoxysqualene mutase (cyclizing, lanosterol-forming)
Systematic name:
(3S)-2,3-epoxy-2,3-dihydrosqualene mutase (cyclizing, lanosterol-forming)

Reaction

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , DIAGRAM , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Protein domains and families: PROSITE:PDOC00825
Structural data: CSA , EC2PDB
Gene Ontology: GO:0000250
CAS Registry Number: 9032-71-7
UniProtKB/Swiss-Prot:

References

  1. Dean, P.D.G., Oritz de Montellano, P.R., Bloch, K. and Corey, E.J.
    A soluble 2,3-oxidosqualene sterol cyclase.
    J. Biol. Chem. 242: 3014-3015 (1967). [PMID: 6027261]

[EC 5.4.99.7 created 1961 as EC 1.99.1.13, transferred 1965 to EC 1.14.1.3, part transferred 1972 to EC 5.4.99.7 rest to EC 1.14.99.7]