EC 5.3.1.8 - Mannose-6-phosphate isomerase

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IntEnz Enzyme Nomenclature
EC 5.3.1.8

Names

Accepted name:
mannose-6-phosphate isomerase
Other names:
D-mannose-6-phosphate ketol-isomerase
mannose phosphate isomerase
phosphohexoisomerase
phosphohexomutase
phosphomannoisomerase
phosphomannose isomerase
Systematic name:
D-mannose-6-phosphate aldose-ketose-isomerase

Reaction

Cofactor

Comments:

A zinc protein.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , DIAGRAM , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , NIST 74 , UniPathway
Protein domains and families: PROSITE:PDOC00746
Structural data: CSA , EC2PDB
Gene Ontology: GO:0004476
CAS Registry Number: 9023-88-5
UniProtKB/Swiss-Prot: (44) [show] [UniProt]

References

  1. Bruns, F.H., Noltmann, E. and Willemsen, A.
    Phosphomannose-isomerase. I. Über die Aktivitätsmessung und die Sulfhydryl-sowie die metallabhängigkeit der Enzymirkung in einigen Tierischen Geweben.
    Biochem. Z. 330: 411-420 (1958). [PMID: 13596383]
  2. Gracy, R.W. and Noltmann, E.A.
    Studies on phosphomannose isomerase. II. Characterization as a zinc metalloenzyme.
    J. Biol. Chem. 243: 4109-4116 (1968). [PMID: 4969968]
  3. Slein, M.W.
    Phosphomannose isomerase.
    J. Biol. Chem. 186: 753-761 (1950). [PMID: 14794671]

[EC 5.3.1.8 created 1961, modified 1976]