EC 5.3.1.13 - Arabinose-5-phosphate isomerase

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IntEnz Enzyme Nomenclature
EC 5.3.1.13

Names

Accepted name:
arabinose-5-phosphate isomerase
Other names:
D-arabinose-5-phosphate ketol-isomerase
arabinose phosphate isomerase
phosphoarabinoisomerase
kdsD (gene name)
gutQ (gene name)
Systematic name:
D-arabinose-5-phosphate aldose-ketose-isomerase

Reaction

Comments:

The enzyme is involved in the pathway for synthesis of 3-deoxy-D-manno-octulosonate (Kdo), a component of bacterial lipopolysaccharides and plant call walls.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , NIST 74 , UniPathway
Protein domains and families: PROSITE:PDOC51464
Structural data: CSA , EC2PDB
Gene Ontology: GO:0019146
CAS Registry Number: 9023-86-3
UniProtKB/Swiss-Prot: (20) [show] [UniProt]

References

  1. Volk, W.A.
    Purification and properties of phosphoarabinoisomerase from Propionibacterium pentosaceum.
    J. Biol. Chem. 235: 1550-1553 (1960).
  2. Lim, R., Cohen, S. S.
    D-phosphoarabinoisomerase and D-ribulokinase in Escherichia coli.
    J. Biol. Chem. 241: 4304-4315 (1966). [PMID: 5332197]
  3. Meredith, T. C., Woodard, R. W.
    Identification of GutQ from Escherichia coli as a D-arabinose 5-phosphate isomerase.
    J. Bacteriol. 187: 6936-6942 (2005). [PMID: 16199563]
  4. Gourlay, L. J., Sommaruga, S., Nardini, M., Sperandeo, P., Deho, G., Polissi, A., Bolognesi, M.
    Probing the active site of the sugar isomerase domain from E. coli arabinose-5-phosphate isomerase via X-ray crystallography.
    Protein Sci. 19: 2430-2439 (2010). [PMID: 20954237]
  5. Chiu, H. J., Grant, J. C., Farr, C. L., Jaroszewski, L., Knuth, M. W., Miller, M. D., Elsliger, M. A., Deacon, A. M., Godzik, A., Lesley, S. A., Wilson, I. A.
    Structural analysis of arabinose-5-phosphate isomerase from Bacteroides fragilis and functional implications.
    Acta Crystallogr. D Biol. Crystallogr. 70: 2640-2651 (2014). [PMID: 25286848]

[EC 5.3.1.13 created 1965]