EC 4.3.2.3 - Ureidoglycolate lyase

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IntEnz Enzyme Nomenclature
EC 4.3.2.3

Names

Accepted name:
ureidoglycolate lyase
Other names:
(S)-ureidoglycolate urea-lyase
ureidoglycolase [ambiguous]
ureidoglycolatase [ambiguous]
ureidoglycolate hydrolase [misleading]
Systematic name:
(S)-ureidoglycolate urea-lyase (glyoxylate-forming)

Reaction

Comments:

This microbial enzyme is involved in the degradation of ureidoglycolate, an intermediate of purine degradation. Not to be confused with EC 3.5.1.116, ureidoglycolate amidohydrolase, which releases ammonia rather than urea.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , DIAGRAM , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , NIST 74 , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0050385
CAS Registry Number: 9014-57-7
UniProtKB/Swiss-Prot: (88) [show] [UniProt]

References

  1. Trijbels, F. and Vogels, G.D.
    Allantoate and ureidoglycolate degradation by Pseudomonas aeruginosa.
    Biochim. Biophys. Acta 132: 115-126 (1967). [PMID: 6030341]
  2. Werner, A. K., Romeis, T., Witte, C. P.
    Ureide catabolism in Arabidopsis thaliana and Escherichia coli.
    Nat. Chem. Biol. 6: 19-21 (2010). [PMID: 19935661]

[EC 4.3.2.3 created 1972, modified 2014]