EC 18.104.22.168 - Formimidoyltetrahydrofolate cyclodeaminase
IntEnz Enzyme Nomenclature
5-formimidoyltetrahydrofolate ammonia-lyase (cyclizing)
22736 [IUBMB]5-formimidoyltetrahydrofolate5-formimidoyltetrahydrofolateName origin: UniProt - CHECKED (C)Formula: C20H22N8O6
Charge: -2ChEBI compound status: CHECKED (C)2H+H(+)Name origin: UniProt - CHECKED (C)Formula: H
Charge: 1ChEBI compound status: CHECKED (C)=5,10-methenyltetrahydrofolate5,10-methenyltetrahydrofolateName origin: UniProt - CHECKED (C)Formula: C20H20N7O6
Charge: -1ChEBI compound status: CHECKED (C)
In eukaroytes, occurs as a bifunctional enzyme that also has glutamate formimidoyltransferase (EC 22.214.171.124) activity.
Links to other databases
Formimino-tetrahydrofolic acid and methenyltetrahydrofolic acid as intermediates in the formation of N10-formyltetrahydrofolic acid.J. Am. Chem. Soc. 78: 5702-5704 (1956).
[EC 126.96.36.199 created 1961, modified 2000]