EC 4.2.1.100 - Cyclohexa-1,5-dienecarbonyl-CoA hydratase

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IntEnz Enzyme Nomenclature
EC 4.2.1.100

Names

Accepted name:
cyclohexa-1,5-dienecarbonyl-CoA hydratase
Other names:
cyclohexa-1,5-diene-1-carbonyl-CoA hydratase
dienoyl-CoA hydratase
cyclohexa-1,5-diene-1-carboxyl-CoA hydratase
cyclohexa-1,5-dienecarbonyl-CoA hydro-lyase [incorrect]
Systematic name:
6-hydroxycyclohex-1-enecarbonyl-CoA hydro-lyase (cyclohexa-1,5-dienecarbonyl-CoA-forming)

Reaction

Comments:

Forms part of the anaerobic benzoate degradation pathway, which also includes EC 1.3.8.6 [glutaryl-CoA dehydrogenase (ETF)], EC 1.3.7.8 (benzoyl-CoA reductase) and EC 4.2.1.55 (3-hydroyxbutyryl-CoA dehydratase).

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UM-BBD , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0018823
UniProtKB/Swiss-Prot:

References

  1. Laempe, D., Eisenreich, W., Bacher, A. and Fuchs, G.
    Cyclohexa-1,5-diene-1-carboxyl-CoA hydratase, an enzyme involved in anaerobic metabolism of benzoyl-CoA in the denitrifying bacterium Thauera aromatica.
    Eur. J. Biochem. 255: 618-627 (1998). [PMID: 9738901]
  2. Harwood, C.S. and Gibson, J.
    Shedding light on anaerobic benzene ring degradation: a process unique to prokaryotes?
    J. Bacteriol. 179: 301-309 (1997). [PMID: 8990279]
  3. Koch, J., Eisenreich, W., Bacher, A. and Fuchs, G.
    Products of enzymatic reduction of benzoyl-CoA, a key reaction in anaerobic aromatic metabolism.
    Eur. J. Biochem. 211: 649-661 (1993). [PMID: 8436125]
  4. Laempe, D., Eisenreich, W., Bacher, A. and Fuchs, G.
    Erratum report. Cyclohexa-1,5-diene-1-carboxyl-CoA hydratase, an enzyme involved in anaerobic metabolism of benzoyl-CoA in the denitrifying bacterium Thauera aromatica.
    Eur. J. Biochem. 257: 528 (1998). [PMID: 8436125]

[EC 4.2.1.100 created 2000, modified 2001]