IntEnz

EC 4.1.2.5 - L-threonine aldolase

IntEnz Enzyme Nomenclature
EC 4.1.2.5

Names

Reaction

• 19625 [IUBMB]
  L-threonine

  L-threonine

  Name origin: UniProt - CHECKED (C)

  CHEBI:57926

  Formula: C4H9NO3
  Charge: 0

  ChEBI compound status: CHECKED (C)

  

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  acetaldehyde

  acetaldehyde

  Name origin: UniProt - CHECKED (C)

  CHEBI:15343

  Formula: C2H4O
  Charge: 0

  ChEBI compound status: CHECKED (C)

  

  +

  glycine

  glycine

  Name origin: UniProt - CHECKED (C)

  CHEBI:57305

  Formula: C2H5NO2
  Charge: 0

  ChEBI compound status: CHECKED (C)

  

Cofactor

• pyridoxal 5'-phosphate

Comments:

A pyridoxal-phosphate protein. This enzyme is specific for L-threonine and can not utilize L-allo-threonine. Different from EC 4.1.2.49, L-allo-threonine aldolase, and EC 4.1.2.48, low-specificity L-threonine aldolase.

Links to other databases

References

1. Bell, S.C. and Turner, J.M.
   Bacterial threonine aldolase and serine hydroxymethyltransferase enzyme.
   Biochem. Soc. Trans. 1: 678-681 (1973).
2. Karasek, M.A. and Greenberg, D.M.
   Studies on the properties of threonine aldolases.
   J. Biol. Chem. 227: 191-205 (1957). [PMID: 13449064]

[EC 4.1.2.5 created 1961, deleted 1972, reinstated 1976, modified 2011]