EC 4.1.1.1 - Pyruvate decarboxylase

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IntEnz Enzyme Nomenclature
EC 4.1.1.1

Names

Accepted name:
pyruvate decarboxylase
Other names:
α-carboxylase [ambiguous]
α-ketoacid carboxylase
pyruvic decarboxylase
2-oxo-acid carboxy-lyase
Systematic name:
2-oxo-acid carboxy-lyase (aldehyde-forming)

Reactions

Cofactor

Comments:

A thiamine-diphosphate protein. Also catalyses acyloin formation.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Protein domains and families: PROSITE:PDOC00166
Structural data: CSA , EC2PDB
Gene Ontology: GO:0004737
CAS Registry Number: 9001-04-1
UniProtKB/Swiss-Prot: (36) [show] [UniProt]

References

  1. Singer, T.P. and Pensky, J.
    Isolation and properties of the α-carboxylase of wheat germ.
    J. Biol. Chem. 196: 375-388 (1952). [PMID: 12980978]

[EC 4.1.1.1 created 1961]