EC 3.6.3.4 - Cu2+-exporting ATPase

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IntEnz Enzyme Nomenclature
EC 3.6.3.4

Names

Accepted name:
Cu2+-exporting ATPase
Other name:
CopB
Systematic name:
ATP phosphohydrolase (Cu2+-exporting)

Reaction

Cofactor

Comments:

A P-type ATPase that undergoes covalent phosphorylation during the transport cycle. The enzyme from the termophilic bacterium Archaeoglobus fulgidus is involved in copper extrusion from the cell [1,2].

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Protein domains and families: PROSITE:PDOC00139
Structural data: CSA , EC2PDB
Gene Ontology: GO:0004008
UniProtKB/Swiss-Prot: (12) [show] [UniProt]

References

  1. Mana-Capelli, S., Mandal, A. K., Arguello, J. M.
    Archaeoglobus fulgidus CopB is a thermophilic Cu2+-ATPase: functional role of its histidine-rich-N-terminal metal binding domain.
    J. Biol. Chem. 278: 40534-40541 (2003). [PMID: 12876283]
  2. Jayakanthan, S., Roberts, S. A., Weichsel, A., Arguello, J. M., McEvoy, M. M.
    Conformations of the apo-, substrate-bound and phosphate-bound ATP-binding domain of the Cu(II) ATPase CopB illustrate coupling of domain movement to the catalytic cycle.
    Biosci. Rep. 32: 443-453 (2012). [PMID: 22663904]

[EC 3.6.3.4 created 2000, modified 2013]