EC 3.5.5.7 - Aliphatic nitrilase

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IntEnz Enzyme Nomenclature
EC 3.5.5.7

Names

Accepted name:
aliphatic nitrilase
Systematic name:
aliphatic nitrile aminohydrolase

Reaction

Comments:

Preferentially hydrolyses aliphatic nitriles, some of which are apparently not substrates for other known nitrilases (EC 3.5.5.1). Substrates include crotononitrile, acrylonitrile and glutaronitrile.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UM-BBD , UniPathway
Protein domains and families: PROSITE:PDOC00712
Structural data: CSA , EC2PDB
Gene Ontology: GO:0018762
CAS Registry Numbers: 143236-44-6 9024-90-2
UniProtKB/Swiss-Prot:

References

  1. Kobayashi, M., Yanaka, N., Nagasawa, T. and Yamada, H.
    Primary structure of an aliphatic nitrile-degrading enzyme, aliphatic nitrilase from Rhodococcus rhodochrous K22 and expression of its gene and identification of its active site residue.
    Biochemistry 31: 9000-9007 (1992). [PMID: 1390687]
  2. Pace, H. C., Brenner, C.
    The nitrilase superfamily: classification, structure and function.
    Genome Biol. 2: 0001.1-0001.9 (2001). [PMID: 11380987]

[EC 3.5.5.7 created 1999]