EC 3.5.4.46 - CAMP deaminase

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IntEnz Enzyme Nomenclature
EC 3.5.4.46

Names

Accepted name:
cAMP deaminase
Other names:
cyclic adenylate deaminase
CadD
Systematic name:
3',5'-cyclic AMP aminohydrolase

Reaction

Cofactor

Comments:

Requires Zn2+. The enzyme, isolated from the bacterium Leptospira interrogans, is specific for cAMP.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB

References

  1. Goble, A. M., Feng, Y., Raushel, F. M., Cronan, J. E.
    Discovery of a cAMP deaminase that quenches cyclic AMP-dependent regulation.
    ACS Chem. Biol. 8: 2622-2629 (2013). [PMID: 24074367]

[EC 3.5.4.46 created 2017]