EC 3.5.2.2 - Dihydropyrimidinase

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IntEnz Enzyme Nomenclature
EC 3.5.2.2

Names

Accepted name:
dihydropyrimidinase
Other names:
D-hydantoinase
hydantoin peptidase
hydantoinase
hydropyrimidine hydrase
pyrimidine hydrase
Systematic name:
5,6-dihydropyrimidine amidohydrolase

Reaction

Comments:

Also acts on dihydrothymine and hydantoin.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , DIAGRAM , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0004157
CAS Registry Number: 9030-74-4
UniProtKB/Swiss-Prot: (12) [show] [UniProt]

References

  1. Brooks, K.P., Jones, E.A., Kim, B.-D. and Sander, E.G.
    Bovine liver dihydropyrimidine amidohydrolase: purification, properties, and characterization as a zinc metalloenzyme.
    Arch. Biochem. Biophys. 226: 469-483 (1983). [PMID: 6639068]
  2. Eadie, G.S., Bernheim, F. and Bernheim, J.L.C.
    Metabolism of cytosine, thymidine, uracil and barbituric acid by bacterial enzymes.
    J. Biol. Chem. 181: 449-458 (1949).

[EC 3.5.2.2 created 1961]