EC 220.127.116.11 - Mitochondrial intermediate peptidase
IntEnz Enzyme Nomenclature
mitochondrial intermediate precursor-processing proteinase
- Release of an N-terminal octapeptide as second stage of processing of some proteins imported into the mitochondrion.
A homologue of thimet oligopeptidase. Natural substrates are precursor proteins that have already been processed by mitochondrial processing peptidase. In peptidase family M3 (thimet oligopeptidase family).
Links to other databases
Amino-terminal octapeptides function as recognition signals for the mitochondrial intermediate peptidase.J. Biol. Chem. 267: 7904-7910 (1992). [PMID: 1560019]
Sequence analysis of rat mitochondrial intermediate peptidase: similarity to zinc metallopeptidases and to a putative yeast homologue.Proc. Natl. Acad. Sci. USA 89: 8317-8321 (1992). [PMID: 1518864]
[EC 18.104.22.168 created 1993]