EC 3.4.21.77 - Semenogelase

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IntEnz Enzyme Nomenclature
EC 3.4.21.77

Names

Accepted name:
semenogelase
Other names:
α-seminoprotein
γ-SM
γ-seminoglycoprotein (human protein moiety reduced)
P-30 antigen
antigen (human clone λHPSA-1 prostate-specific protein moiety reduced)
antigen PSA (human clone 5P1 protein moiety reduced)
antigen PSA (human prostate-specific)
human glandular kallikrein
prostate-specific antigen
seminin
Systematic name:

Reaction

Comments:

A peptidase of family S1 (trypsin family) from seminal plasma. Slowly inhibited by α1-antichymotrypsin.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , MEROPS , UniPathway
Protein domains and families: PROSITE:PDOC00124
Structural data: CSA , EC2PDB
CAS Registry Numbers: 110157-83-0 95829-41-7
UniProtKB/Swiss-Prot:

References

  1. Digby, M., Zhang, X.-Y. and Richards, R.I.
    Human prostate specific antigen (PSA) gene: structure and linkage to the kallikrein-like gene, hGK-1.
    Nucleic Acids Res. 15: 2137 (1989). [PMID: 2467258]
  2. Christensson, A., Laurell, C.-B. and Lilja, H.
    Enzymatic activity of prostate-specific antigen and its reactions with extracellular serine proteinase inhibitors.
    Eur. J. Biochem. 194: 755-763 (1990). [PMID: 1702714]

[EC 3.4.21.77 created 1993]