EC 22.214.171.124 - Protein C (activated)
IntEnz Enzyme Nomenclature
activated blood coagulation factor XIV
activated protein C
blood-coagulation factor XIVa
- Degradation of blood coagulation factors Va and VIIIa.
A peptidase of family S1 (trypsin family), one of the γ-carboxyglutamic acid-containing coagulation factors. Formed from protein C, the proenzyme that circulates in plasma, by the action of a complex of thrombin with thrombomodulin, or by serine endopeptidases present in several snake venoms.
Links to other databases
The regulation of natural anticoagulant pathways.Science 235: 1348-1352 (1987). [PMID: 3029867]
The roles of protein C and thrombomodulin in the regulation of blood coagulation.J. Biol. Chem. 264: 4743-4746 (1989). [PMID: 2538457]
[EC 126.96.36.199 created 1992]