EC - Cathepsin G

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IntEnz Enzyme Nomenclature


Accepted name:
cathepsin G
Other names:
chymotrypsin-like proteinase
neutral proteinase
Systematic name:



From azurophil granules of polymorphonuclear leukocytes. In peptidase family S1 (trypsin family).

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , MEROPS , UniPathway
Protein domains and families: PROSITE:PDOC00124
Structural data: CSA , EC2PDB
Gene Ontology: GO:0004261
CAS Registry Number: 56645-49-9


  1. Barrett, A.J.
    Cathepsin G.
    Methods Enzymol. 80C: 561-565 (1981). [PMID: 7341917]
  2. Tanaka, T., Minematsu, Y., Reilly, C.F., Travis, J. and Powers, J.C.
    Human leukocyte cathepsin G. Subsite mapping with 4-nitroanilides, chemical modification, and effect of possible cofactors.
    Biochemistry 24: 2040-2047 (1985). [PMID: 4016099]
  3. Hohn, P.A., Popescu, N.C., Hanson, R.D., Salvesen, G. and Ley, T.J.
    Genomic organization and chromosomal localization of the human cathepsin G gene.
    J. Biol. Chem. 264: 13412-13419 (1989). [PMID: 2569462]

[EC created 1978]