EC 3.4.13.9 - Xaa-Pro dipeptidase

  IntEnz view ENZYME view

IntEnz Enzyme Nomenclature
EC 3.4.13.9

Names

Accepted name:
Xaa-Pro dipeptidase
Other names:
γ-peptidase
X-Pro dipeptidase
imidodipeptidase
peptidase D
prolidase
proline dipeptidase
Systematic name:
-

Reaction

Cofactor

Comments:

A Mn2+-activated enzyme, in peptidase family M24 (methionyl aminopeptidase family); cytosolic from most animal tissues. Formerly EC 3.4.3.7.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , MEROPS , UniPathway
Protein domains and families: PROSITE:PDOC00417
Structural data: CSA , EC2PDB
Gene Ontology: GO:0004251 , GO:0102009
CAS Registry Number: 9025-32-5
UniProtKB/Swiss-Prot: (118) [show] [UniProt]

References

  1. Davis, N.C. and Smith, E.L.
    Purification and some properties of prolidase of swine kidney.
    J. Biol. Chem. 224: 261-275 (1957). [PMID: 13398404]
  2. Sjöström, H., Norén, O. and Josefsson, L.
    Purification and specificity of pig intestinal prolidase.
    Biochim. Biophys. Acta 327: 457-470 (1973). [PMID: 4778946]
  3. Baksi, K. and Radhakrishnan, A.N.
    Purification and properties of prolidase (imidodipeptidase) from monkey small intestine.
    Indian J. Biochem. Biophys. 44: 7-11 (1974). [PMID: 4435812]
  4. Browne, P. and O'Cuinn, G.
    The purification and characterization of a proline dipeptidase from guinea pig brain.
    J. Biol. Chem. 258: 6147-6154 (1983). [PMID: 6853481]

[EC 3.4.13.9 created 1961 as EC 3.4.3.7, transferred 1972 to EC 3.4.13.9]