EC - β-Ala-His dipeptidase

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IntEnz Enzyme Nomenclature


Accepted name:
β-Ala-His dipeptidase
Other name:
serum carnosinase
Systematic name:



Present in the serum of humans and higher primates, but not in the serum of other mammals. Activated by Cd2+ and citrate.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , MEROPS , UniPathway
Structural data: CSA , EC2PDB
CAS Registry Number: 9027-21-8


  1. Lenney, J.F., George, R.P., Weiss, A.M., Kucera, C.M., Chan, P.W.H. and Rinzler, G.S.
    Human serum carnosinase: characterization, distinction from cellular carnosinase, and activation by cadmium.
    Clin. Chim. Acta 123: 221-231 (1982). [PMID: 7116644]
  2. Jackson, M.C., Kucera, C.M. and Lenney, J.F.
    Purification and properties of human serum carnosinase.
    Clin. Chim. Acta 196: 193-206 (1991). [PMID: 1903095]

[EC created 1992]