EC 3.4.11.3 - Cystinyl aminopeptidase

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IntEnz Enzyme Nomenclature
EC 3.4.11.3

Names

Accepted name:
cystinyl aminopeptidase
Other names:
L-cystine aminopeptidase
cystine aminopeptidase
cystyl-aminopeptidase
oxytocin peptidase
oxytocinase
vasopresssinase
Systematic name:
-

Reaction

Cofactor

Comments:

A zinc-containing sialoglycoprotein in peptidase family M1 (membrane alanyl aminopeptidase family).

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , MEROPS , UniPathway
Structural data: CSA , EC2PDB
CAS Registry Number: 9031-41-8
UniProtKB/Swiss-Prot:

References

  1. Sjöholm, I.
    Biochemical studies on oxytocin and oxytocinase.
    Acta Pharm. Suec. 4: 81-96 (1967). [PMID: 6041057]
  2. Sjöholm, I. and Yman, L.
    Degradation of oxytocin, lysine vasopressin, angiotensin II, and angiotensin II amide by oxytocinase (cystine aminopeptidase).
    Acta Pharm. Suec. 4: 65-76 (1967). [PMID: 4292447]
  3. Yman, L.
    Studies on human serum aminopeptidase. Some properties of oxytocinase, human serum aminopeptidase A and leucine aminopeptidase and their purification from retroplacental serum.
    Acta Pharm. Suec. 7: 75-86 (1970). [PMID: 5421622]
  4. Sakura, H., Lin, T.Y., Doi, M., Mizutani, S. and Kawashima, Y.
    Purification and properties of oxytocinase, a metalloenzyme.
    Biochem. Int. 2: 173-179 (1981).

[EC 3.4.11.3 created 1972]