EC 3.2.1.23 - β-galactosidase

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IntEnz Enzyme Nomenclature
EC 3.2.1.23

Names

Accepted name:
β-galactosidase
Other names:
β-D-galactanase
β-D-lactosidase
β-lactosidase
S 2107
hydrolact
lactase
lactozym
maxilact
oryzatym
sumiklat
trilactase
exo-(1→4)-β-D-galactanase
Systematic name:
β-D-galactoside galactohydrolase

Reaction

Comments:

Some enzymes in this group hydrolyse α-L-arabinosides; some animal enzymes also hydrolyse β-D-fucosides and β-D-glucosides; cf. EC 3.2.1.108 lactase.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , NIST 74 , UniPathway
Protein domains and families: PROSITE:PDOC00495 , PROSITE:PDOC00531 , PROSITE:PDOC00910
Structural data: CSA , EC2PDB
Gene Ontology: GO:0004565
CAS Registry Number: 9031-11-2
UniProtKB/Swiss-Prot: (195) [show] [UniProt]

References

  1. Blakely, J.A. and MacKenzie, S.L.
    Purification and properties of a β-hexosidase from Sporobolomyces singularis.
    Can. J. Biochem. 47: 1021-1025 (1969). [PMID: 5389663]
  2. Kuby, S.A. and Lardy, H.A.
    Purification and kinetics of β-D-galactosidase from Escherichia coli, strain K-12.
    J. Am. Chem. Soc. 75: 890-896 (1953).
  3. Kuo, C.H. and Wells, W.W.
    β-Galactosidase from rat mammary gland. Its purification, properties, and role in the biosynthesis of 6β-O-D-galactopyranosyl myo-inositol.
    J. Biol. Chem. 253: 3550-3556 (1978). [PMID: 418065]
  4. Landman, O.E.
    Properties and induction of β-galactosidase in Bacillus megaterium.
    Biochim. Biophys. Acta 23: 558-569 (1957). [PMID: 13426167]
  5. Llanillo, M., Perez, N. and Cabezas, J.A.
    β-Galactosidase and β-glucosidase activities of the same enzyme from rabbit liver.
    Int. J. Biochem. 8: 557-564 (1977).
  6. Monod, J. and Cohn, M.
    La biosynthèse induite des enzymes (adaptation enzymatique).
    Adv. Enzymol. Relat. Subj. Biochem. 13: 67-119 (1952). [PMID: 14943665]
  7. Wallenfels, K. and Malhotra, O.P.
    β-Galactosidase
    In: Boyer, P.D., Lardy, H. and Myrbäck, K. (Eds.) The Enzymes, 2nd ed. vol. 4, Academic Press, New York, 1960, 409-430
  8. Asp, N.G., Dahlqvist, A. and Koldovský, O.
    Human small-intestinal β-galactosidases. Separation and characterization of one lactase and one hetero β-galactosidase.
    Biochem. J. 114: 351-359 (1969). [PMID: 5822067]

[EC 3.2.1.23 created 1961, modified 1980]