EC 3.2.1.1 - α-amylase

  IntEnz view ENZYME view

IntEnz Enzyme Nomenclature
EC 3.2.1.1

Names

Accepted name:
α-amylase
Other names:
α amylase
Taka-amylase A
alpha-amylase
endoamylase
glycogenase
1,4-α-D-glucan glucanohydrolase
Systematic name:
4-α-D-glucan glucanohydrolase

Reaction

Comments:

Acts on starch, glycogen and related polysaccharides and oligosaccharides in a random manner; reducing groups are liberated in the α-configuration. The term "α" relates to the initial anomeric configuration of the free sugar group released and not to the configuration of the linkage hydrolysed.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , NIST 74 , UniPathway
Protein domains and families: PROSITE:PDOC51166
Structural data: CSA , EC2PDB
Gene Ontology: GO:0004556 , GO:0103025
CAS Registry Number: 9000-90-2
UniProtKB/Swiss-Prot: (133) [show] [UniProt]

References

  1. Fischer, E.H. and Stein, E.A.
    α-Amylases.
    In: Boyer, P.D., Lardy, H. and Myrbäck, K. (Eds.) The Enzymes, 2nd ed. vol. 4, Academic Press, New York, 1960, 313-343
  2. Manners, D.J.
    Enzymic synthesis and degradation of starch and glycogen.
    Adv. Carbohydr. Chem. 17: 371-430 (1962).
  3. Schwimmer, S. and Balls, A.K.
    Isolation and properties of crystalline α-amylase from germinated barley.
    J. Biol. Chem. 179: 1063-1074 (1949). [PMID: 18134570]

[EC 3.2.1.1 created 1961]