EC - Iduronate-2-sulfatase

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IntEnz Enzyme Nomenclature


Accepted name:
Other names:
2-sulfo-L-iduronate 2-sulfatase
L-iduronate 2-sulfate sulfatase
L-idurono sulfate sulfatase
iduronate sulfatase
iduronate sulfate sulfatase
iduronate-2-sulfate sulfatase
iduronide-2-sulfate sulfatase
sulfo-L-iduronate sulfatase
sulfoiduronate sulfohydrolase
Systematic name:
L-iduronate-2-sulfate 2-sulfohydrolase


Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Protein domains and families: PROSITE:PDOC00117
Structural data: CSA , EC2PDB
Gene Ontology: GO:0004423
CAS Registry Number: 50936-59-9


  1. Archer, I.M., Harper, P.S. and Wusteman, F.S.
    Multiple forms of iduronate 2-sulphate sulphatase in human tissues and body fluids.
    Biochim. Biophys. Acta 708: 134-140 (1982). [PMID: 6816283]
  2. Bach, J., Eisenberg, F., Cantz, M. and Neufeld, E.C.
    The defect in the Hunter syndrome: deficiency of sulfoiduronate sulfatase.
    Proc. Natl. Acad. Sci. USA 70: 2134-2138 (1973). [PMID: 4269173]
  3. DiNatale, P. and Ronsivalle, L.
    Identification and partial characterization of two enzyme forms of iduronate sulfatase from human placenta.
    Biochim. Biophys. Acta 661: 106-111 (1981). [PMID: 6945876]
  4. Yutaka, T., Fluharty, A.L., Stevens, R.L. and Kihara, H.
    Purification and some properties of human liver iduronate sulfatase.
    J. Biochem. (Tokyo) 91: 433-441 (1982). [PMID: 6950934]

[EC created 1984]