EC 3.1.11.3 - Exodeoxyribonuclease (lambda-induced)

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IntEnz Enzyme Nomenclature
EC 3.1.11.3

Names

Accepted name:
exodeoxyribonuclease (lambda-induced)
Other names:
E. coli exonuclease IV
Escherichia coli exonuclease IV
exodeoxyribonuclease IV
exonuclease IV
lambda exonuclease
phage lambda-induced exonuclease
Systematic name:

Reaction

Comments:

Preference for double-stranded DNA. Does not attack single-strand breaks. Formerly EC 3.1.4.28.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
CAS Registry Number: 37367-70-7
UniProtKB/Swiss-Prot:

References

  1. Lindahl, T., Gally, J.A. and Edelman, G.M.
    Deoxyribonuclease IV: a new exonuclease from mammalian tissues.
    Proc. Natl. Acad. Sci. USA 62: 597-603 (1969). [PMID: 5256235]
  2. Little, J.W.
    An exonuclease induced by bacteriophage lambda. II. Nature of the enzymatic reaction.
    J. Biol. Chem. 242: 679-686 (1967). [PMID: 6017737]

[EC 3.1.11.3 created 1972 as EC 3.1.4.28, transferred 1978 to EC 3.1.11.3]