EC 3.1.1.8 - Cholinesterase

  IntEnz view ENZYME view

IntEnz Enzyme Nomenclature
EC 3.1.1.8

Names

Accepted name:
cholinesterase
Other names:
BtChoEase
pseudocholineesterase
benzoylcholinesterase
butyrylcholine esterase
butyrylcholinesterase
choline esterase
choline esterase II (unspecific)
non-specific cholinesterase
propionylcholinesterase
pseudocholinesterase
Systematic name:
acylcholine acylhydrolase

Reaction

Comments:

Acts on a variety of choline esters and a few other compounds.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Protein domains and families: PROSITE:PDOC00112
Structural data: CSA , EC2PDB
Gene Ontology: GO:0004104
CAS Registry Number: 9001-08-5
UniProtKB/Swiss-Prot: (14) [show] [UniProt]

References

  1. Augustinsson, K.-B.
    Cholinesterases. A study in comparative enzymology.
    Acta Physiol. Scand. (1948).
  2. Augustinsson, K.-B. and Olsson, B.
    Esterases in the milk and blood of swine. I. Substrate specificity and electrophoresis studies.
    Biochem. J. 71: 477-484 (1959).
  3. Koelle, G.B.
    Cholinesterases of the tissues and sera of rabbits.
    Biochem. J. 53: 217-226 (1953).
  4. Nachmansohn, D. and Wilson, I.B.
    The enzymic hydrolysis and synthesis of acetylcholine.
    Adv. Enzymol. Relat. Subj. Biochem. 12: 259-339 (1951).
  5. Sawyer, C.H.
    Hydrolysis of choline esters by liver.
    Science 101: 385-386 (1945).
  6. Strelitz, F.
    Studies on cholinesterase. 4. Purification of pseudo-cholinesterase from horse serum.
    Biochem. J. 38: 86-88 (1944).

[EC 3.1.1.8 created 1961]