EC 3.1.1.59 - Juvenile-hormone esterase

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IntEnz Enzyme Nomenclature
EC 3.1.1.59

Names

Accepted name:
juvenile-hormone esterase
Other names:
JH-esterase
juvenile hormone analog esterase
juvenile hormone carboxyesterase
JH esterase
methyl-(2E,6E)-(10R,11S)-10,11-epoxy-3,7,11-trimethyltrideca-2,6-dienoate acylhydrolase
Systematic name:
methyl-(2E,6E,10R)-10,11-epoxy-3,7,11-trimethyltrideca-2,6-dienoate acylhydrolase

Reactions

Comments:

Demethylates the insect juvenile hormones, JH1 and JH3, but does not hydrolyse the analogous ethyl or isopropyl esters.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , DIAGRAM , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Protein domains and families: PROSITE:PDOC00112
Structural data: CSA , EC2PDB
Gene Ontology: GO:0004453
UniProtKB/Swiss-Prot:

References

  1. de Kort, C.A.D. and Granger, N.A.
    Regulation of the juvenile hormone titer.
    Annu. Rev. Entomol. 26: 1-28 (1981).
  2. Mitsui, T., Riddiford, L.M. and Bellamy, G.
    Metabolism of juvenile hormone by the epidermis of the tobacco hornworm (Manduca sexta).
    Insect Biochem. 9: 637-643 (1979).

[EC 3.1.1.59 created 1989, modified 2015]