EC - Chlorophyllase

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IntEnz Enzyme Nomenclature


Accepted name:
Other names:
Systematic name:
chlorophyll chlorophyllidohydrolase



Chlorophyllase has been found in higher plants, diatoms, and in the green algae Chlorella [3]. This enzyme forms part of the chlorophyll degradation pathway and is thought to take part in de-greening processes such as fruit ripening, leaf senescence and flowering, as well as in the turnover and homeostasis of chlorophyll [4]. This enzyme acts preferentially on chlorophyll a but will also accept chlorophyll b and pheophytins as substrates [5]. Ethylene and methyl jasmonate, which are known to accelerate senescence in many species, can enhance the activity of the hormone-inducible form of this enzyme [5].

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , DIAGRAM , DIAGRAM , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0047746 , GO:0102293
CAS Registry Number: 9025-96-1


  1. Holden, M.
    The breakdown of chlorophyll by chlorophyllase.
    Biochem. J. 78: 359-364 (1961). [PMID: 13715233]
  2. Klein, A.O. and Vishniac, W.
    Activity and partial purification of chlorophyllase in aqueous systems.
    J. Biol. Chem. 236: 2544-2547 (1961). [PMID: 13756631]
  3. Tsuchiya, T., Ohta, H., Okawa, K., Iwamatsu, A., Shimada, H., Masuda, T. and Takamiya, K.
    Cloning of chlorophyllase, the key enzyme in chlorophyll degradation: finding of a lipase motif and the induction by methyl jasmonate.
    Proc. Natl. Acad. Sci. USA 96: 15362-15367 (1999). [PMID: 10611389]
  4. Okazawa, A., Tango, L., Itoh, Y., Fukusaki, E. and Kobayashi, A.
    Characterization and subcellular localization of chlorophyllase from Ginkgo biloba.
    Z. Naturforsch. C: Biosci. 61: 111-117 (2006). [PMID: 16610227]
  5. Hörtensteiner, S.
    Chlorophyll degradation during senescence.
    Annu. Rev. Plant Biol. 57: 55-77 (2006). [PMID: 16669755]

[EC created 1961, modified 2007]