EC - Butyrate—acetoacetate CoA-transferase

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IntEnz Enzyme Nomenclature


Accepted name:
butyrate—acetoacetate CoA-transferase
Other names:
butyryl coenzyme A—acetoacetate coenzyme A-transferase
butyryl-CoA—acetoacetate CoA-transferase
Systematic name:
butanoyl-CoA:acetoacetate CoA-transferase



Butanoate, acetoacetate and their CoA thioesters are the preferred substrates, but the enzyme also acts, more slowly, on the derivatives of a number of C2 to C6 monocarboxylic acids.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Protein domains and families: PROSITE:PDOC00980
Structural data: CSA , EC2PDB
Gene Ontology: GO:0047371
CAS Registry Number: 66231-37-6


  1. Barker, H.A., Jeng, I.-M., Neff, N., Robertson, J.M., Tam, F.K. and Hosaka, S.
    Butyryl-CoA:acetoacetate CoA-transferase from a lysine-fermenting Clostridium.
    J. Biol. Chem. 253: 1219-1225 (1978). [PMID: 624727]

[EC created 1984]