EC 2.8.2.21 - Keratan sulfotransferase

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IntEnz Enzyme Nomenclature
EC 2.8.2.21

Names

Accepted name:
keratan sulfotransferase
Other names:
3'-phosphoadenylyl keratan sulfotransferase
3'-phosphoadenylylsulfate:keratan sulfotransferase
keratan sulfate sulfotransferase
Systematic name:
3'-phosphoadenylyl-sulfate:keratan 6'-sulfotransferase

Reaction

Comments:

Sulfation takes place at the 6-position of galactosyl and N-acetylglucosaminyl residues in keratan, a proteoglycan. Not identical with EC 2.8.2.5 (chondroitin 4-sulfotransferase), EC 2.8.2.6 (choline sulfotransferase) or EC 2.8.2.17 (chondroitin 6-sulfotransferase).

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0045130
CAS Registry Number: 62168-79-0
UniProtKB/Swiss-Prot:

References

  1. Ruter, E.-R. and Kresse, H.
    Partial purification and characterization of 3'-phosphoadenylylsulfate:keratan sulfate sulfotransferases.
    J. Biol. Chem. 259: 11771-11776 (1984). [PMID: 6592165]

[EC 2.8.2.21 created 1989]