EC 2.7.7.8 - Polyribonucleotide nucleotidyltransferase

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IntEnz Enzyme Nomenclature
EC 2.7.7.8

Names

Accepted name:
polyribonucleotide nucleotidyltransferase
Other names:
PNPase
nucleoside diphosphate:polynucleotidyl transferase
polynucleotide phosphorylase
polyribonucleotide nucleotidyltransferase
polyribonucleotide phosphorylase
Systematic name:
polyribonucleotide:phosphate nucleotidyltransferase

Reaction

Comments:

ADP, IDP, GDP, UDP and CDP can act as donors.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ERGO , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0004654
CAS Registry Number: 9014-12-4
UniProtKB/Swiss-Prot: (782) [show] [UniProt]

References

  1. Hakim, A.A.
    Synthetic activity of polynucleotide phosphorylase from sperm.
    Nature 183: 334 (1959).
  2. Littauer, U.Z. and Kornberg, A.
    Reversible synthesis of polyribonucleotides with an enzyme from Escherichia coli.
    J. Biol. Chem. 226: 1077-1092 (1957).
  3. Ochoa, S. and Mii, S.
    Enzymatic synthesis of polynucleotides. IV. Purification and properties of polynucleotide phosphorylase from Azotobacter vinelandii.
    J. Biol. Chem. 236: 3303-3311 (1961).

[EC 2.7.7.8 created 1961]