IntEnz

EC 2.7.7.52 - RNA uridylyltransferase

IntEnz Enzyme Nomenclature
EC 2.7.7.52

Names

Reaction

• 14785 [IUBMB]
  RNA_(n)

  RNA(n)

  POLYMER:11128

  Formula: HO(C5H7O6PR)_n
  Charge: (-1)(-1)_n

  ChEBI polymer: CHEBI:83400

  

  +

  UTP

  UTP

  Name origin: UniProt - CHECKED (C)

  CHEBI:46398

  Formula: C9H11N2O15P3
  Charge: -4

  ChEBI compound status: CHECKED (C)

  

  <?>

  diphosphate

  diphosphate

  Name origin: UniProt - CHECKED (C)

  CHEBI:33019

  Formula: HO7P2
  Charge: -3

  ChEBI compound status: CHECKED (C)

  

  +

  RNA_(n+1)

  RNA(n+1)

  POLYMER:11129

  Formula: HO(C5H7O6PR)_n+1
  Charge: (-1)(-1)_n+1

  ChEBI polymer: CHEBI:83400

  

Comments:

The enzyme requires an oligoribonucleotide or polyribonucleotide with a free terminal 3'-OH as a primer.

Links to other databases

References

1. Zabel, P., Dorssers, L., Wernars, K. and van Kammen, A.
   Terminal uridylyl transferase of Vigna unguiculata: purification and characterization of an enzyme catalyzing the addition of a single UMP residue to the 3'-end of an RNA primer.
   Nucleic Acids Res. 9: 2433-2453 (1981). [PMID: 6269049]

[EC 2.7.7.52 created 1983]