EC - Glucose-1-phosphate thymidylyltransferase

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IntEnz Enzyme Nomenclature


Accepted name:
glucose-1-phosphate thymidylyltransferase
Other names:
TDP-glucose pyrophosphorylase
dTDP-glucose pyrophosphorylase
dTDP-glucose synthase
glucose 1-phosphate thymidylyltransferase
thymidine diphosphate glucose pyrophosphorylase
thymidine diphosphoglucose pyrophosphorylase
dTDP-glucose diphosphorylase
Systematic name:
dTTP:α-D-glucose-1-phosphate thymidylyltransferase


Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , DIAGRAM , ERGO , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , NIST 74 , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0008879
CAS Registry Number: 9026-03-3
UniProtKB/Swiss-Prot: (23) [show] [UniProt]


  1. Kornfeld, S. and Glaser, L.
    The enzymic synthesis of thymidine-linked sugars. I. Thymidine diphosphate glucose.
    J. Biol. Chem. 236: 1791-1794 (1961). [PMID: 13753209]
  2. Pazur, J.H. and Shuey, E.W.
    The enzymatic synthesis of thymidine diphosphate glucose and its conversion to thymidine diphosphate rhamnose.
    J. Biol. Chem. 236: 1780-1785 (1961). [PMID: 13733719]
  3. Zuccotti, S., Zanardi, D., Rosano, C., Sturla, L., Tonetti, M., Bolognesi, M.
    Kinetic and crystallographic analyses support a sequential-ordered bi bi catalytic mechanism for Escherichia coli glucose-1-phosphate thymidylyltransferase.
    J. Mol. Biol. 313: 831-843 (2001). [PMID: 11697907]

[EC created 1965]