EC 2.7.1.49 - Hydroxymethylpyrimidine kinase

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IntEnz Enzyme Nomenclature
EC 2.7.1.49

Names

Accepted name:
hydroxymethylpyrimidine kinase
Other name:
hydroxymethylpyrimidine kinase (phosphorylating)
Systematic name:
ATP:4-amino-5-hydroxymethyl-2-methylpyrimidine 5-phosphotransferase

Reaction

Comments:

CTP, UTP and GTP can act as donors.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0008902
CAS Registry Number: 9026-55-5
UniProtKB/Swiss-Prot: (32) [show] [UniProt]

References

  1. Lewin, L.M. and Brown, G.M.
    The biosynthesis of thiamine. III. Mechanism of enzymatic formation of the pyrophosphate ester of 2-methyl-4-amino-5-hydroxymethylpyrimidine.
    J. Biol. Chem. 236: 2768-2771 (1961).

[EC 2.7.1.49 created 1965]