EC 2.7.1.36 - Mevalonate kinase

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IntEnz Enzyme Nomenclature
EC 2.7.1.36

Names

Accepted name:
mevalonate kinase
Other names:
ATP:mevalonate 5-phosphotransferase
MVA kinase
mevalonate 5-phosphotransferase
mevalonate kinase (phosphorylating)
mevalonate phosphokinase
mevalonic acid kinase
mevalonic kinase
Systematic name:
ATP:(R)-mevalonate 5-phosphotransferase

Reaction

Comments:

CTP, GTP and UTP can also act as donors.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , DIAGRAM , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Protein domains and families: PROSITE:PDOC00545
Structural data: CSA , EC2PDB
Gene Ontology: GO:0004496
CAS Registry Number: 9026-52-2
UniProtKB/Swiss-Prot: (20) [show] [UniProt]

References

  1. Hellig, H. and Popják, G.
    Studies on the biosynthesis of cholesterol. XIII. Phosphomevalonic kinase from liver.
    J. Lipid Res. 2: 235-243 (1961).
  2. Levy, G.B. and Popják, G.
    Studies on the biosynthesis of cholesterol. 10. Mevalonic kinase from liver.
    Biochem. J. 75: 417-428 (1960).
  3. Markley, K. and Smallman, E.
    Mevalonic kinase in rabbit liver.
    Biochim. Biophys. Acta 47: 327-335 (1961).
  4. Tchen, T.T.
    Mevalonic kinase: purification and properties.
    J. Biol. Chem. 233: 1100-1103 (1958). [PMID: 13598740]

[EC 2.7.1.36 created 1961]