EC 2.7.1.147 - ADP-specific glucokinase

  IntEnz view ENZYME view

IntEnz Enzyme Nomenclature
EC 2.7.1.147

Names

Accepted name:
ADP-specific glucokinase
Other name:
ADP-dependent glucokinase
Systematic name:
ADP:D-glucose 6-phosphotransferase

Reaction

Cofactor

Comments:

Requires Mg2+. The enzyme from Pyrococcus furiosus is highly specific for D-glucose; there is some activity with 2-deoxy-D-glucose, but no activity with D-fructose, D-mannose or D-galactose as the substrate. No activity is detected when ADP is replaced by ATP, GDP, phosphoenolpyruvate, diphosphate or polyphosphate.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0043843
UniProtKB/Swiss-Prot: (11) [show] [UniProt]

References

  1. Kengen, S.W., Tuininga, J.E., de Bok, F.A., Stams, A.J. and de Vos, W.M.
    Purification and characterization of a novel ADP-dependent glucokinase from the hyperthermophilic archaeon Pyrococcus furiosus.
    J. Biol. Chem. 270: 30453-30457 (1995). [PMID: 8530474]

[EC 2.7.1.147 created 2001]